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Table 1 Summary of cases of B. Cereus reported in previously healthy individuals

From: Survival of community-acquired Bacillus cereus sepsis with venous sinus thrombosis in an immunocompetent adult man – a case report and literature review

No

Year

Sex

Age

Profession

Basic disease

Symptoms on presentation

Diagnosis

Pathogen detection method

Treatment (antibiotics)

Outcome

Reference (PMID)

1

1985

M

67

Engineer

cardiac failure

Retrosternal and right pleural pain

Pleuropulmonary infection

Pleural fluid cultures

GEN, CFZ, ERY

Death

3,936,280

2

1985

M

18

Student

No

Fever, cough, hemoptysis

Pneumonia

Sputum and blood cultures

CLDM, ERY, AMP

Survival

3,919,626

3

1991

M

21

Unknown

Bronchiectasia

Fever, cough, chills

Pneumonia

Sputum and BALF cultures

CPFX

Survival

1,902,995

4

1997

M

17

Student

No

Vomiting, lethargy, jaundice, abdominal pain

Fulminant hepatic failure, rhabdomyolysis, and acute renal failure

Intestinal contents and pan residue cultures

Untreated by antibiotics

Death

9,099,658

5

1997

M

46

Welder

No

Fever, cough, hemoptysis, vomiting

Bacteremia Pneumonia

Sputum and blood cultures

CPFX, CTX

Death

9,003,628

6

1997

M

41

Welder

No

Fever, cough, hemoptysis

Bacteremia Pneumonia

Sputum and blood cultures

AMP/SUL, ERY, CLDM, VAN

Death

9,003,628

7

2002

M

29

Unknown

No

Left leg erythema papules, ulceration

Skin soft-tissue infection

Tissue cultures

CPFX

Recovery

12140490 [11]

8

2003

M

76

Unknown

Abdominal operation

Fever and shock occurred 17 days after surgery

BSI

Blood culture and central venous tip cultures

PIP/TZP

Recovery

14,616,690

9

2008

F

69

Unknown

Diabetes, hypertension

Difficulty breathing, sweating, weight loss

Endocarditis

Blood cultures

CFZ

Recovery

18706120 [16]

10

2008

F

9

Student

No

Abdominal pain vomiting diarrhea, convulsions, coma, shock

Gastroenteritis, liver failure

Food cultures

MEM, CLDM

Recovery

18,664,929

11

2011

M

20

Student

No

Headache, nausea, vomiting, abdominal pain, diarrhea

Gastroenteritis, liver necrosis, colon necrosis

Faeces cultures

Untreated

Death

22,012,017

12

2010

M

11

Student

No

Abdominal cramps, vomiting, lethargy, convulsions

Gastroenteritis, liver failure, encephalopathy

Gastric juice, leftover race and faeces cultures

Untreated by antibiotics

Recovery

19796886 [17]

13

2011

M

74

Unknown

Valvular history, coronary stent history

Fever, dyspnea, night sweats, shock

BSI

Blood and bone marrow cultures

VAN, CPFX

Death

22173364 [9]

14

2016

M

59

Mechanic

No

Fatigue, nausea, indigestion, weight loss

Liver abscess

Puncture drainage fluid cultures

VAN, LEV

Recovery

28025629 [18]

15

2017

F

81

Unknown

Atrial fibrillation, Cardiac failure

Fever, cough, respiratory distress

Pneumonia, BSI

Blood sample cultures

IPM, LEV

Recovery

29457069 [19]

16

2019

F

32

Unknown

Abdominal trauma

Fever 48 h after surgery

Liver abscess, BSI

Drainage fluid and blood cultures

AMP/SUL, VAN

Recovery

31,791,818

17

2019

M

60

Unknown

Hypertension

Hemoptysis, respiratory distress, chest pain, right shoulder and right abdominal pain, numbness in the right hand

Necrotic hemorrhagic pneumonia

Sputum cultures

Untreated by antibiotics

Death

30813918 [13]

18

2019

M

91

Unknown

End-stage renal disease

High fever, shortness of breath, shock, ARDS

Aortic aneurysm

Blood cultures

VAN, CTRX,

Recovery

31,711,418

19

2020

M

58

School principal

Diabetes

Intermittent low fever, painless hematuria, oliguria, weight loss, focal epilepsy

Infective endocarditis, cerebral hemorrhage, splenic abscess

Identified by BD Phoenix

CPFX

Recovery

32655954 [12]

20

2020

F

40

Unknown

No

Vomiting, abdominal pain, syncope

Sepsis, multi-organ failure, shock, metabolic acidosis, rhabdomyolysis, coagulopathy,

Mass spectrometry (Bruker)

PIP/TZP, MNZ, AZI, VAN, MEM

Death

33462030 [20]

21

2021

M

25

Chef

No

Nausea, vomiting, diarrhea, abdominal pain

Gastroenteritis, liver failure

Leftover rice cultures

PIP/TZP

Recovery

35050989 [21]

22

2022

F

27

Unknown

No

Fever Abdominal pain vomiting diarrhea

Malaria, Gastroenteritis

Blood cultures

VAN/levofloxacin

Recovery

36,712,755

23

2022

No

80

Unknown

pituitary tumor

Abdominal pain vomiting diarrhea

meningoencephalitis

Blood cultures, broad-range 16 s rDNA PCR

VAN

Recovery

35,880,229

24

2022

F

33

Unknown

No

small vesicles, itching

cutaneous infection

broad-range 16 s rDNA PCR

CPFX

Recovery

35,448,975

25

2023

F

40

Unknown

type 1 bipolar disorder, major depressive disorder (MDD), migraines without aura, hypothyroidism,

severe headache

meningoencephalitis

Blood cultures, cerebrospinal fluid cultures

VAN

Survival

36,788,826

  1. AMP Ampicillin, AZI Azithromycin, AMP&SUL Ampicillin/sulbactam, CFZ Cefazolin, CTX Cefotaxime, CTRX Ceftriaxone, CLDM Clindamycin, CPFX Ciprofloxacin, ERY Erythromycin, GEN Gentamicin, IPM Imipenem, LEV Levofloxacin, MEM Meropenem, MNZ Metronidazole, PIP/TZP Piperacillin/tazobactam, VAN Vancomycin