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Table 1 Compiled eligible studies included in the meta-analysis of rk39 in Ethiopia

From: Performance of rapid rk39 tests for the diagnosis of visceral leishmaniasis in Ethiopia: a systematic review and meta-analysis

Author Year TP FN FP TN Ref. test Sample type Control group Sens (95% CI) Spec (95% CI)
Asrat et al. HIV- (DiaMed) 2014 80 2 2 109 DAT Serum Healthy non-endemic, Healthy endemic & Other disease control 0.976 (0.98–0.99) 0.982 (0.93–0.99)
Asrat et al. HIV- (InBios) 2014 77 5 2 109 DAT Serum Healthy non-endemic, Healthy endemic & Other disease control 0.939 (0.88–0.97) 0.982 (0.98–0.93)
Asrat et al. HIV + (DiaMed) 2014 12 1 0 0 DAT Serum Healthy non-endemic, Healthy endemic & Other disease control 0.893 (0.60–0.98) 0.500 (0.02–0.98)
Asrat et al. HIV + (InBios) 2014 11 2 0 0 DAT Serum Healthy non-endemic & Healthy endemic & Other disease control 0.821 (0.54–0.95) 0.500 (0.02–0.98)
Boelaert et al. (InBios) 2008 15 5 5 10 DAT Serum Endemic patient control 0.750 (0.52–0.89) 0.667 (0.41–0.85)
Carmen et al. (DiaMed) 2011 32 3 4 63 Microscopy Serum Healthy endemic control 0.914 (0.77–0.97) 0.940 (0.85–0.98)
Carmen et al. (InBios) 2011 33 2 1 66 Microscopy Serum Health endemic control 0.943 (0.80–0.99) 0.985 (0.90–0.99)
Diro et al. (DiaMed) 2015 165 22 72 104 Microscopy&NNN Serum Endemic patient control 0.882 (0.83–0.92) 0.591 (0.52–0.66)
Diro et al. (InBios) 2007 35 14 9 43 Microscopy&NNN Serum Endemic patient control 0.714 (0.57–0.82) 0.827 (0.70–0.91)
Kiros et al.(InBios) 2017 37 7 13 5 Microscopy Serum Endemic patient control 0.841 (0.70–0.92) 0.278 (0.12–0.52)
ter Horst et al. HIV + (DiaMed) 2009 136 32 2 9 Micoscopy Dried blood spot(DBS) Other diseased patients 0.810 (0.74–0.86) 0.818 (0.49–0.95)
ter Horst et al. HIV- (DiaMed) 2009 42 23 2 4 Microscopy DBS Other diseased patients 0.646 (0.52–0.75) 0.667 (0.27–0.92)
Sarfaraz et al. (InBios) 2019 85 1 0 0 Microscopy Serum Other diseased patient & healthy endemic 0.983 (0.92–0.99) 0.500 (0.02–0.98)
Getachew et al. (DiaMed) 2019 11 0 46 304 *ELISA Whole blood Endemic Patient control 0.958 (0.58–0.99) 0.868 (0.82–0.90)
Endalamaw et al. (InBios) 2012 2 6 0 23 DAT DBS Endemic patient control 0.278 (0.08–0.62) 0.979 (0.74–0.99)
Canavate et al. (Diamed) 2011 223 23 0 0 PCR Serum Healthy endemic 0.905 (0.86–0.94) 0.500 (0.02–0.98)
Canavate et al. (Inbios) 2011 219 27 0 0 PCR Serum Healthy endemic 0.889 (0.84–0.92) 0.500 (0.02–0.98)
Alelign et al. (InBios) 2020 106 4 11 75 Micoscopy Serum Other diseased patient & healthy control 0.96 (0.91–0.99) 0.87 (0.78–0.93)