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Table 2 Demographic and clinical characteristics of the study cohort

From: Dengue in Western Uganda: a prospective cohort of children presenting with undifferentiated febrile illness

Characteristic All Malaria RDT Positive Malaria RDT Negative p-Value
Patients (n, %) 1693 (100) 369 (21.8) 1324 (78.2)
Age, (median, IQR) 5 (2–10) 7 (4–11) 4 (2–9) < 0.001*
 < 5 years 788 (46.5) 122 (33.1) 666 (50.3)  
 5–12 years 577 (34.1) 155 (42.0) 422 (31.9) < 0.001
 ≥ 12 years 328 (19.4) 92 (24.9) 236 (17.8)  
Female sex (n, %) 904 (53.4) 200 (54.2) 704 (53.2) 0.73
Recruitment Site (n, %)
 Bugoye 632 (37.3) 214 (58.0) 418 (31.6)  
 Kasese 606 (35.8) 138 (37.4) 468 (35.4) < 0.001
 Mbarara 455 (26.9) 17 (4.6) 438 (33.1)  
Slept under bednet (n, %) 1222 (73.0) 244 (67.2) 978 (74.5) 0.005
 Excluding Mbarara 858 (70.3) 235 (67.9) 623 (71.3) 0.25
Days since fever onset
(median, IQR)*
3 (2–3) 3 (2–3) 3 (2–3) 0.0008*
Reported Symptoms
 Anorexia/Poor Feeding 234 (13.8) 56 (15.2) 178 (13.4) 0.39
 Arthralgia 170 (10.0) 64 (17.3) 106 (8.0) < 0.001
 Cough 1178 (69.1) 208 (56.1) 970 (72.7) < 0.001
 Diarrhea 234 (13.8) 34 (9.2) 200 (15.1) 0.004
 Headache 1076 (63.6) 276 (74.8) 800 (60.4) < 0.001
 Myalgia 143 (8.5) 59 (16.0) 84 (6.3) < 0.001
 Rash 92 (5.4%) 15 (4.1) 77 (5.8) 0.19
 Rhinorrhea 897 (53.0) 134 (36.3) 763 (57.6) < 0.001
 Seizures 6 (0.4) 1 (0.3) 5 (0.4) 0.76
 Vomiting 248 (14.7) 46 (12.5) 202 (15.3) 0.18
Abnormal Vital Signs (n, %)
 Febrile (T ≥ 38o C) 281 (16.6) 75 (20.3) 206 (15.6) 0.03
 Hypoxia (SpO2 < 90%) 93 (5.5) 12 (3.3) 81 (6.2) 0.03
Previously seen at health center for same condition? 252 (15.0) 30 (8.2) 222 (16.8) < 0.001
Taken antimalarials in the last 2 weeks? 175 (10.4) 26 (7.1) 149 (11.3) 0.02
  1. Abbreviations: RDT Rapid diagnostic test, IQR Interquartile range, Co Degrees celsisus, SpO2 Oxygen saturation as measured by pulse oximeter. *Determined using Wilcoxon Rank Sum