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Table 3 Covariate analysis of total cholesterol (TC), HDL-cholesterol (HDL), TC/HDL ratio, LDL-cholesterol (LDL), tryglicerides (TG) and Framingham risk score (FRS), according to confounding factors used in the multivariable analysis: all confounders and treatment groups were included at the same time

From: Improvement of lipid profile after switching from efavirenz or ritonavir-boosted protease inhibitors to rilpivirine or once-daily integrase inhibitors: results from a large observational cohort study (SCOLTA)

 

TC

HDL

TC/HDL

LDL

TG

FRS

Age (b-value, by 1)

0.3 p = 0.09

0.0 P = 0.92

0.0 P = 0.45

0.27 P = 0.10

0.1 P = 0.89

Sex (b-value, F vs M)

6.6 P = 0.10

3.4 P = 0.007

−0.24 P = 0.07

1.7 P = 0.65

2.8 P = 0.77

Diabetes (b-value, Y vs N)

−9.7 P = 0.22

0.9 P = 0.68

−0.3 P = 0.24

−7.4 P = 0.34

14.5 P = 0.43

Statins (b-value, Y vs N)

−10.1 P = 0.08

−1.3 P = 0.41

−0.0 P = 0.66

−7.8 P = 0.15

1.1 P = 0.93

−0.35 0.62

ART duration (b-value, by 1)

−0.2 P = 0.34

−0.1 P = 0.37

− 0.0 P = 0.86

−0.0 P = 0.84

− 0.4 P = 0.52

0.02 P = 0.58

Baseline value (b-value, by 1)

− 0.4 P < 0.0001

−0.3 P < 0.0001

− 0.43 P < 0.0001

−0.43 P < 0.0001

− 0.5 p < 0.0001

−0.02 P = 0.32

  1. F female, M male, Y yes, N no, ART antiretroviral therapy