Table 4 Mean annual OI prevalence (per 1000) in a cohort of HIV positive individuals before and after HAART in Uganda
From: Trends in prevalence of selected opportunistic infections associated with HIV/AIDS in Uganda
| Â | Before HAART | Early HAART | Late HAART | Â | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OI | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | X 2 trend (p-value) |
Cryptococcal meningitis | 5.5 | 5.4 | 2.5 | 3.3 | 2.7 | 2.7 | 1.6 | 1.2 | 4.0 | 1.3 | 1.3 | 0.23 | 1.79 (0.1807) |
% change | - | 0 | −54 | +32 | −18 | 0 | −41 | −25 | +233 | −67 | 0 | −82 |  |
Mycobacterium tuberculosis | 76.9 | 45.5 | 29.3 | 16.2 | 9.6 | 13.2 | 9.0 | 10.9 | 9.1 | 7.4 | 6.6 | 11.0 | 157.38 (<0.0001) |
% change | - | −41 | −36 | −45 | −41 | +37 | −32 | +21 | −16 | −19 | −11 | +67 |  |
Herpes zoster | 13.4 | 13.9 | 11.5 | 9.1 | 7.6 | 10.0 | 5.1 | 5.0 | 3.8 | 3.7 | 3.7 | 3.3 | 13.67 (0.0002) |
% change | - | +4 | −14 | −25 | 11 | +37 | −54 | 2 | −24 | −20 | 0 | −11 |  |
Oral candida | 172.7 | 106.4 | 83.1 | 32.3 | 26.5 | 20.0 | 17.0 | 12.0 | 12.6 | 15.4 | 8.7 | 6.7 | 458.20 (<0.0001) |
% change | - | −38.7 | −20 | −62 | −16 | −26 | −10 | −33 | +8 | −23 | −37 | −20 |  |
Genital ulcer(HSV-2) | 15.1 | 18.2 | 17.6 | 12.3 | 9.3 | 12.0 | 11.2 | 8.1 | 9.2 | 7.2 | 7.7 | 8.9 | 8.8 (0.0029) |
% change | - | +21 | 3.3 | −33 | −17 | +20 | −8 | 27 | +25 | −20 | −12.5 | +43 |  |