A matched cross-sectional study of the association between circulating tissue factor activity, immune activation and advanced liver fibrosis in hepatitis C infection

Table 3 Association between tissue factor detection and CD4 T-cell immune activation

CD4 T-cell marker	Percent expression in patients with:		p-value
	Detectable TF	Undetectable TF
HLADR+	43.8 ± 9.8	36.2 ± 11.0	0.05
TotalCD38+	15.2 ± 6.4	19.5 ± 9.1	0.16
CD38 + HLADR+	5.7 ± 2.9	5.5 ± 2.8	0.85
CD38-HLADR+	38.2 ± 8.7	30.7 ± 10.4	0.04
CD38 + HLADR-	9.6 ± 3.7	14.0 ± 7.4	0.01
CD45RA + CCR7-	8.3 ± 6.3	13.3 ± 6.8	0.04
CD45RA-CCR7+	19.9 ± 5.2	19.9 ± 5.2	0.99
CD45RA + CCR7+	18.4 ± 12.1	18.8 ± 10.1	0.91
CD45RA-CCR7-	53.4 ± 15.4	48.0 ± 12.3	0.23

Results reported as mean ± standard deviation.
CD45RA + CCR7-, terminal effectors expressing RA (TEMRA); CD45RA-CCR7+, Central Memory; CD45RA + CCR7+, naïve; CD45RA-CCR7-, effector memory; TF, tissue factor

ISSN: 1471-2334