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Table 2 Effluent antifungal concentration and negative-pressure wound therapy parameters

From: Antifungal wound penetration of amphotericin and voriconazole in combat-related injuries: case report

    

Amphotericin B (μg/mL)

Voriconazole (μg/mL)

Patient

Site

Pressure (mmHg)

Effluent (mL)

Total

Free

Total

Free

1

Abd

−125

14

0.3

<LOD

--

--

 

LLQ

−125

37

0.2

<LOD

--

--

2a

Arm

−125

96

3.0 ± 0.4

<LOD

2.7 ± 0.2

1.5 ± 0.002

 

Abd

−125

60

1.3 ± 0.1

<LOD

1.6 ± 0.2

1.2 ± 0.01

 

Heel

−125

28

1.3 ± 0.1

<LOD

0.6 ± 0.1

0.6 ± 0.01

  1. LOD, limit of detection (2.5 ng/mL). Abd, abdomen; LLQ, left lower quadrant; LOD, limit of detection.