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Table 2 Clinical characteristics of children with invasive S. aureus infections

From: Clinical and molecular characteristics of invasive community-acquired Staphylococcus aureusinfections in Chinese children

Characteristics

Total n =163 N (%)

MRSA n =71 N (%)

MSSA n = 92 N (%)

P

Infection sites a

    

Bacteremia

107 (65.6)

34 (47.9)

73 (79.3)

0.000

Pneumonia

86 (52.8)

43 (60.6)

43 (46.7)

0.08

Severe pneumonia

72 (83.7)

38 (88.4)

34 (79.1)

0.243

 Necrotizing pneumonia

16 (18.6)

8 (18.6)

8 (18.6)

1.0

Moderate pneumonia

14 (16.3)

5 (11.6)

9 (20.9)

0.243

Musculoskeletal infection

32 (19.6)

8 (11.3)

24 (26.1)

0.018

 Osteomyelitis

27 (84.3)

8 (100)

19 (79.2)

0.29

 Arthritis

15 (46.9)

3 (37.5)

17 (70.8)

0.116

 Pyomyositis

10 (31.2)

4 (50)

6 (25)

1.0

 Necrotizing fasciitis

8 (25)

2 (25)

6 (25)

1.0

Meningitis

7 (3.7)

3 (4.2)

4 (4.3)

1.0

Endocarditis

3 (1.8)

2 (2.8)

1 (1.1)

0.82

Orbital abscess

4 (2.5)

4 (5.6)

0

0.073

Deep-seated abscess

4 (2.5)

1 (1.4)

3 (3.3)

0.805

Othersb

6 (3.6)

4 (5.6)

2 (2.2)

0.457

Clinical diagnosis

    

Single-site infections

51 (31.3)

29 (40.8)

22 (23.9)

0.021

Pneumonia

23 (45.1)

18 (62.1)

5 (22.7)

0.005

Bacteremia

15 (29.4)

6 (20.7)

9 (40.9)

0.117

Musculoskeletal infection

7 (13.7)

2 (6.9)

5 (22.7)

0.224

Othersc

6 (11.8)

3 (10.3)

3 (13.6)

1.0

Multi-site infections

112 (68.7)

42 (59.2)

70 (76.1)

0.021

Two infection sites

87 (77.7)

35 (49.3)

52 (74.3)

0.266

Bacteremia + SSTI

22 (19.6)

10 (23.8)

12 (17.1)

0.39

Bacteremia + Pneumonia

29 (25.9)

7 (16.7)

22 (31.4)

0.084

 Bacteremia-related Pneumonia

16 (14.3)

3 (7.1)

13 (18.6)

0.094

 Pneumonia-related Bacteremia

13 (11.6)

4 (9.5)

9 (12.9)

0.594

Bacteremia + Musculoskeletal infection

12 (10.7)

2 (4.8)

10 (14.3)

0.207

Pneumonia + SSTI

10 (8.9)

9 (21.4)

1 (1.4)

0.001

Othersd

14 (12.5)

7 (16.7)

7 (10)

0.302

The infection sites ≥3

25 (22.3)

7 (16.7)

18 (25.7)

0.266

Bacteremia + Pneumonia + SSTI

12 (10.7)

2 (4.8)

10 (14.3)

0.207

Otherse

13 (11.6)

5 (11.9)

8 (11.4)

1.00

  1. MRSA: methicillin-resistant S. aureus; MSSA: methicillin-susceptible S. aureus; SSTI: skin and soft tissue infections.
  2. aNot mutually exclusive.
  3. bOne MRSA case each of lymphadenitis, peritonitis, hepatapostema, and appendiceal abscess and one MSSA case each of peritonitis and hydrocele complicated with infection.
  4. cOne MRSA case each of appendiceal abscess, deep-seated abscess, and orbital abscess and three MSSA cases of deep-seated abscess.
  5. dTwo MRSA cases of bacteremia + orbital abscess, one MRSA case each of pneumonia + musculoskeletal infection, pneumonia + meningitis, pneumonia + peritonitis, pneumonia + hepatapostema, and musculoskeletal infection + SSTI; three MSSA cases of musculoskeletal infection + SSTI; one MSSA case each of pneumonia + meningitis, bacteremia + peritonitis, endocarditis + meningitis, and bacteremia + hydrocele complicated with infection.
  6. eOne MRSA case each of bacteremia + meningitis + endocarditis, bacteremia + pneumonia + lymphadenitis, pneumonia + musculoskeletal infection + endocarditis, bacteremia + pneumonia + orbital abscess + meningitis, and bacteremia + pneumonia + musculoskeletal infection + SSTI; four MSSA cases of bacteremia + musculoskeletal infection + SSTI; two cases of bacteremia + pneumonia + meningitis + SSTI; one MSSA case each of bacteremia + pneumonia + musculoskeletal infection and bacteremia + pneumonia + musculoskeletal infection + SSTI.
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BMC Infectious Diseases

ISSN: 1471-2334

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