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Table 1 Demographic details and lavage cell counts at recruitment. Demographic details and radiographic scores are of 15 patients with pulmonary tuberculosis with their matched controls; the lavage cell counts are those of 10 patients and 6 controls. All participants were recruited in London, United Kingdom.

From: The pathogen recognition sensor, NOD2, is variably expressed in patients with pulmonary tuberculosis

Numbers in parenthesis indicate %

TB

Control

Age (median; range in years)

28; 18–52

28; 19–48

Sex (male)

9 (60)

8 (53)

Ethnicity

  

   Black African

9 (60)

8 (53)

   Indian

4 (26)

4 (26)

   Other

2 (14)

3 (21)

X-ray features

  

Cavitation

8 (53)

0

>50% airspace shadowing of total lung field

7 (47)

0

BAL (mean ± SE)

  

Total leucocytes (× 104/ml)

31 ± 8

12.8 ± 4.2

lymphocyte count (× 104/ml)

15 ± 4

2.7 ± 1.4

CD4: CD8 ratio

3.8 ± 1

2.55 ± 0.9

IFN-γ copy number

3390 [1525–7498]

13 [4–113]; p = 0.0005

Th1/Th2 ratio

3.5 [3.1–3.8]

1.1 [.4–1.8]; p = 0.0007