Volume 14 Supplement 2

Abstracts from the International Symposium HIV and Emerging Infectious Diseases 2014

Open Access

Epidemiological aspects of new HIV/AIDS diagnoses in south-east Romania

  • M Arbune1,
  • C Georgescu1,
  • D Tutunaru1,
  • M Dobre1 and
  • A Nechita1
BMC Infectious Diseases201414(Suppl 2):P53

https://doi.org/10.1186/1471-2334-14-S2-P53

Published: 23 May 2014

Introduction

The characteristic of HIV/AIDS Romanian epidemic is the high proportion of youth infected in 1988-1990, during their first year of life, when a nosocomial epidemiological accident took place. In Galati (South-East Romania) they were recorded 535 people with HIV/AIDS during 1990-2003 and 79.5% belonged to the pediatric nosocomial cohort. The mortality was 56.8% and half of the deaths were recorded during the first year after diagnosis. The aim of the study is to identify the changes in the HIV/AIDS epidemic in the last 10 years.

Materials and methods

This retrospective study was based on epidemiological reports of the newly diagnosed HIV/AIDS patients. The descriptive statistics and comparative Kaplan-Meier graphs by transmission way were analyzed using XL-Stat Software.

Results

During 2004-2013, 182 new patients have been diagnosed with HIV/AIDS in Galati. Most patients are young people with the same age as the pediatric cohort of HIV/ AIDS, but predominance of heterosexual transmission marks the change of the epidemic pattern. (table 1). Late presentation is less associated with sexual than other transmission ways (p=0.026), but is most likely expected in males (p=0,003), with symptomatic context (p<0,001). Death rate is 15%. Retention in care was achieved in 95% of cases. Tuberculosis is still the leading indicator of AIDS (21.4%). Tuberculosis (12/26) and cancer disease (6/26) are the main causes of death.
Table 1

Characteristics of new HIV/AIDS diagnosed patients in Galati

Median diagnostic age:

23[1;78]

Sex: Male/ Female

98/84

Area: Urban/ Rural

87/95

Transmission:

 

Perinatally

4.4%

Nozocomial

19.8%

Heterosexual

56%

MSM

1.6%

IVDU

3.8%

Unknown

14.3%

Context of HIV testing:

 

HIV partner

17.6%

Pregnancy

11.5%

Perinatal exposure

3.6%

Drugs users

1.6%

Other screening programs

8.2%

Symptomatic:

51.2%

Clinical CDC-class: A/B/C

19/81/83

Immunological-class:1/2/3

27/52/103

Conclusions

The life expectancy of HIV/AIDS patients has obviously improved in the last decade, but the yearly number of new cases is constant, with a high rate of late presenters. The strategy of future screening programs should consider the trends of HIV/AIDS epidemic in our region.

Authors’ Affiliations

(1)
"Dunarea de Jos" University

Copyright

© Arbune et al; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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