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Table 5 Cytokine production by splenocyte a cultures from immunized BALB/c mice

From: Toxoplasma gondii cathepsin proteases are undeveloped prominent vaccine antigens against toxoplasmosis

Group

Cytokine production (pg/mL)b

 

IFN-γ

IL-4

IL-10

PBS

47.59 ± 4.63

37.26 ± 2.84

44.34 ± 2.77

PBudCE4.1

48.35 ± 1.86

33.70 ± 3.29

38.70 ± 2.70

pTgCPB

674.93 ± 83.36*

32.58 ± 3.72

34.60 ± 1.92

pTgCPL

585.14 ± 112.03*

32.34 ± 3.87

35.47 ± 1.94

pTgCPB/TgCPL

1182.23 ± 94.28*#

36.11 ± 3.51

34.57 ± 2.14

  1. IFN, interferon; IL, interleukin, PBS, phosphate-buffered saline.
  2. a Splenocytes were obtained from 3 mice per group and were collected at week 4 after the final immunization.
  3. b Values for IFN-γ at 96 h. Values for IL-10 at 72 h. Values for IL-4 at 24 h.
  4. *Compared with the PBS-adjuvant or pBudCE4.1 controls (P < 0.05); # compared with pTgCPB or pTgCPB (P < 0.05).
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BMC Infectious Diseases

ISSN: 1471-2334

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