Skip to main content

Table 2 Factors associated with a positive T-SPOT.TB in 43 patients with determinate test results. Univariate and multivariate analysis

From: Improved sensitivity of an interferon-gamma release assay (T-SPOT.TB™) in combination with tuberculin skin test for the diagnosis of latent tuberculosis in the presence of HIV co-Infection

Variable

Univariate analysis

Multivariate analysis

  

OR

95% CI

p-value

Adjusted OR

95% CI

p-value

Age, per 10 years older

1.02

0.52-2.03

0.945

1.23

0.53-2.87

0.624

Female

0.78

0.21-2.89

0.707

1.36

0.17-11.1

0.775

Body mass index, per 5 kg/m2 increase

0.62

0.20-1.89

0.403

0.59

0.18-2.00

0.398

Non-white ethnicity

1.70

0.50-5.83

0.397

-

-

-

Risk

Men who have sex with men

1*

-

-

-

-

-

 

Heterosexual

1.04

0.22-4.91

0.960

-

-

-

 

Intravenous drug use

1.40

0.23-8.46

0.714

-

-

-

Prior AIDS-defining condition

0.65

0.16-2.70

0.553

-

-

-

Antiretroviral treatment

0.31

0.26-1.21

0.120

0.87

0.14-5.65

0.888

CD4 cell count, per 50 cells/μL increase

1.01

0.85-1.20

0.904

-

-

-

CD4 cell count ≥200 versus < 200 cells/μL

2.55

0.72-8.96

0.146

1.41

0.27-7.39

0.682

CD8 cell count, per 50 cells/μL increase

0.97

0.93-1.02

0.292

-

-

-

Positive TST (≥ 5 mm)

1.63

0.40-6.63

0.493

-

-

-

Extrapulmonary versus pulmonary TB

2.13

0.61-7.41

0.237

-

-

-

Time between cells freezing and IGRA performance, per month

0.99

0.98-1.01

0.453

-

-

-

  1. * Reference category