Variable | Positive T-SPOT.TB | Negative T-SPOT.TB | Indeterminate T-SPOT.TB | p-value | ||||
---|---|---|---|---|---|---|---|---|
N = 25 | N = 18 | N = 21 | ||||||
n | % | n | % | n | % | |||
Median age, IQR (years) | 35 | 32-40 | 36 | 30-43 | 35 | 29-44 | 0.915 | |
Males | 18 | 72 | 12 | 67 | 14 | 67 | 0.904 | |
Median body mass index, IQR (kg/m2) | 22 | 20-25 | 22 | 21-25 | 23 | 20-26 | 0.906 | |
White ethnicity | 13 | 52 | 7 | 39 | 9 | 53 | 0.670 | |
Prior AIDS-defining condition | 5 | 20 | 5 | 25 | 8 | 38 | 0.396 | |
Risk | MSM | 5 | 20 | 4 | 22 | 7 | 28 | 0.978 |
Heterosexual | 13 | 52 | 10 | 56 | 4 | 22 | ||
Intravenous drug use | 7 | 38 | 10 | 48 | 5 | 24 | ||
TB disease | Pulmonary | 13 | 52 | 7 | 39 | 13 | 62 | 0.357 |
Extrapulmonary | 8 | 32 | 9 | 50 | 7 | 33 | ||
Pulmonary and extrapulmonary | 4 | 16 | 2 | 11 | 1 | 5 | ||
Median CD4 cell count at TB diagnosis, IQR (cells/μL) | 235 | 106-330 | 169 | 70-297 | 229 | 130-300 | 0.572 | |
Median HIV-RNA at TB diagnosis, IQR (log10 copies/mL) | 4.7 | 3.5-5.6 | 5.0 | 4.6-5.2 | 4.9 | 4.6-5.3 | 0.531 | |
Median CD4 cell count at cells sampling, IQR (cells/μL) | 235 | 122-320 | 147 | 70-349 | 256 | 108-379 | 0.498 | |
Median CD8 cell count at cells sampling, IQR (cells/μL) | 614 | 448-889 | 842 | 460-1191 | 835 | 510-1417 | 0.308 | |
Median HIV-RNA at cells sampling, IQR (log10 copies/mL) | 4.8 | 3.2-5.3 | 4.9 | 4.6-5.0 | 4.6 | 4.3-5.1 | 0.868 | |
Antiretroviral therapy at cells sampling | 13 | 52 | 14 | 78 | 12 | 57 | 0.211 | |
Time between cells sampling and TB diagnosis, IQR (days) | 63 | 15-126 | 57 | 12-163 | 72 | 20-284 | 0.786 | |
Time between cells sampling and performance of IGRA, IQR (months) | 81 | 48-135 | 107 | 70-141 | 123 | 84-167 | 0.142 | |
TST | ≥ 5 mm | 10 | 40 | 7 | 39 | 5 | 24 | 0.414 |
< 5 mm | 7 | 28 | 8 | 44 | 7 | 33 | ||
missing | 8 | 32 | 3 | 17 | 9 | 43 |