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Table 1 Patient characteristics

From: Imbalances in serum angiopoietin concentrations are early predictors of septic shock development in patients with post chemotherapy febrile neutropenia

Characteristics Sepsis ¥
(n = 31)
Septic shock
(n = 10)
P
Sex (male:female) 13:18 7:3 0.16 **
Age (median, range) 37 (16-55) 55 (24-62) P < 0.01 *
Diagnosis
Acute leukemias 17 4  
Other 14 6  
Disease status    0.12 **
Complete remission 13 (42%) 1 (10%)  
Active disease 18 (58%) 9 (90%)  
Treatment    0.48 **
Intensive CTx/autologous HSCT 17 6  
Allogeneic HSCT 14 4  
Neutrophils/μl - Fever (median, range) 60 (0 - 290) 50 (20 - 470) 0.40 *
Days of neutropenia (median, range) 12 (4 - 22) 14 (7 - 30) 0.36 *
Platelets × 10 3 /μl - fever (median, range) 25 (6 - 169) 38 (12 - 90) 0.16 *
Days with fever (median, range) 4 (1 - 12) 5 (1 - 12) 0.65 *
SOFA score - fever onset (median, range) 3 (0 - 7) 4 (2 - 8 ) 0.31 *
SOFA score - 48 hours (median, range) 4 (2 - 7) 7 (4 - 16) P = 0.01 *
MASCC score (median, range) 21 (16 - 23) 18 (11 - 24) P = 0.03 *
Agent isolation in bloodstream (yes:no) £ 4:27 8:2 P < 0.001 **
Von Willebrand Factor U/ml - fever (median, range) 205.12(88.94 -341.95) 262.72 (208.19-430.09) 0.11 *
  1. ¥ Non-complicated sepsis; *Mann-Whitney test; **Fisher's exact test; €: Lymphoma (n = 8); Multiple Myeloma (n = 5); Myeloproliferative diseases (n = 5); Paroxysmal Nocturnal Hemoglobinuria (n = 2); HSCT: Hematopoietic stem cell transplantation; CTx: chemotherapy. £: Gram negative: n = 7; Gram positive: 7; Fungi: n = 2 (4 patients with mixed flora infections).