Characteristics | Sepsis ¥ (n = 31) | Septic shock (n = 10) | P |
---|---|---|---|
Sex (male:female) | 13:18 | 7:3 | 0.16 ** |
Age (median, range) | 37 (16-55) | 55 (24-62) | P < 0.01 * |
Diagnosis | |||
Acute leukemias | 17 | 4 | Â |
Other € | 14 | 6 |  |
Disease status | Â | Â | 0.12 ** |
Complete remission | 13 (42%) | 1 (10%) | Â |
Active disease | 18 (58%) | 9 (90%) | Â |
Treatment | Â | Â | 0.48 ** |
Intensive CTx/autologous HSCT | 17 | 6 | Â |
Allogeneic HSCT | 14 | 4 | Â |
Neutrophils/μl - Fever (median, range) | 60 (0 - 290) | 50 (20 - 470) | 0.40 * |
Days of neutropenia (median, range) | 12 (4 - 22) | 14 (7 - 30) | 0.36 * |
Platelets × 10 3 /μl - fever (median, range) | 25 (6 - 169) | 38 (12 - 90) | 0.16 * |
Days with fever (median, range) | 4 (1 - 12) | 5 (1 - 12) | 0.65 * |
SOFA score - fever onset (median, range) | 3 (0 - 7) | 4 (2 - 8 ) | 0.31 * |
SOFA score - 48 hours (median, range) | 4 (2 - 7) | 7 (4 - 16) | P = 0.01 * |
MASCC score (median, range) | 21 (16 - 23) | 18 (11 - 24) | P = 0.03 * |
Agent isolation in bloodstream (yes:no) £ | 4:27 | 8:2 | P < 0.001 ** |
Von Willebrand Factor U/ml - fever (median, range) | 205.12(88.94 -341.95) | 262.72 (208.19-430.09) | 0.11 * |