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Table 3 Predictors of overall complications in hospitalized IBD patients

From: Adequate antiviral treatment lowers overall complications of cytomegalovirus colitis among inpatients with inflammatory bowel diseases

Characteristics

Univariable analysis

 

Multivariable analysis

 

OR

95% CI

p-value

 

OR

95% CI

p-value

Age (years)

0.994

(0.972–1.015)

0.564

    

Gender (Male)

0.403

(0.182–0.893)

0.025*

 

0.449

(0.188–1.072)

0.071

BMI

1.039

(0.943–1.146)

0.441

    

CMV colitis

1.185

(0.556–2.524)

0.661

 

3.532

(1.012–12.331)

0.048*

Laboratory data

       

 WBC

0.964

(0.873–1.063)

0.461

    

 Haemoglobin

0.924

(0.788–1.083)

0.329

    

 CRP

1.000

(0.99–1.01)

0.978

    

 Albumin

1.018

(0.535–1.937)

0.956

    

IBD duration (months)

1.007

(0.999–1.015)

0.072

 

1.005

(0.997–1.013)

0.256

Clinical presentation

       

 Bloody stool

0.632

(0.291–1.374)

0.247

    

 Diarrhoea

0.499

(0.233–1.068)

0.073

    

 Pain

0.966

(0.456–2.044)

0.928

    

 Fever

0.978

(0.356–2.684)

0.965

    

IBD Medication

       

 Biological failure

3.484

(1.492–8.134)

0.004*

 

4.953

(1.91–12.842)

0.001*

 Biologics user

1.575

(0.707–3.509)

0.266

    

 5-ASA

2.153

(0.49–9.458)

0.310

    

 Oral prednisolone

0.684

(0.33–1.42)

0.308

    

 Azathioprine

0.869

(0.386–1.957)

0.735

    

 Antibiotics

0.592

(0.272–1.288)

0.186

    

Antiviral treatment ≧ 14 days

0.613

(0.268–1.402)

0.247

 

0.108

(0.023–0.512)

0.005*

  1. Overall, the IBD complications included strictures, abscesses, fistulas, colon cancer, and IBD-related surgeries. Abbreviations: ALT, Alanine aminotransferase; 5-ASA, 5-aminosalicylic acid; BMI, body mass index; CDAI, Crohn’s Disease Activity Index; CI, confidence interval; CMV, cytomegalovirus; CRP, C-reactive protein; IBD, inflammatory bowel disease; OR, odds ratio; WBC, white blood cell; *p < 0.05, calculated using logistic regression analysis