| | | Gene expression | Serum |
|---|
Variable | CB2 | MOR | IL-17 | MCP-1 | OPN | IFN-γ |
|---|
Gene expression | | | | | | | |
CB2 | | | | | | |
Correlation | 1 | 0.541** | 0.249 | 0.335** | 0.261* | 0.394** |
P value | | 0 | 0.053 | 0.008 | 0.042 | 0.002 |
MOR | | | | | | |
Correlation | 0.541** | 1 | 0.206 | 0.322* | 0.231 | 0.424** |
P value | 0 | | 0.112 | 0.011 | 0.073 | 0.001 |
Serum | | | | | | | |
IL-17 | | | | | | |
Correlation | 0.249 | 0.206 | 1 | 0.636** | 0.476** | 0.482** |
P value | 0.053 | 0.112 | | 0 | 0 | 0 |
MCP-1 | | | | | | |
Correlation | 0.335** | 0.322* | 0.636** | 1 | 0.441** | 0.646** |
P value | 0.008 | 0.011 | 0 | | 0 | 0 |
OPN | | | | | | |
Correlation | 0.261* | 0.231 | 0.476** | 0.441** | 1 | 0.636** |
P value | 0.042 | 0.073 | 0 | 0 | | 0 |
IFN-γ | | | | | | |
Correlation | 0.394** | 0.424** | 0.482** | 0.646** | 0.636** | 1 |
P value | 0.002 | 0.001 | 0 | 0 | 0 | |
- **. Correlation is significant at the 0.01 level (2-tailed). *. Correlation is significant at the 0.05 level (2-tailed)
- Table 3 presents the correlation coefficients and corresponding P values for the relationships between CB2, MOR, IL-17, MCP-1, OPN, and IFN-γ. Key points to note include:
- Significant correlations (**P < 0.01, *P < 0.05) are denoted by the respective symbols
- The correlation values indicate the strength and direction of the relationships between the variables
- CB2 and MOR show significant correlations with IL-17, MCP-1, OPN, and IFN-γ, providing insights into their interplay in the context of SARS-CoV-2 infection severity. The analysis method employed for calculating these correlations was Pearson analysis
- These correlation results contribute to understanding the potential interactions and associations among the studied biomarkers, shedding light on their roles in the pathophysiology of SARS-CoV-2
