Effect of concurrent infection of Helicobacter pylori with Toxoplasma gondii infection on gastric pathology

BMC Infectious Diseases

Table 4 Histopathological findings in the different genotypes of virulence strains of H. pylori

		H.pylori gene			P-value
		Vac As1 N = 37	Vac As1+ Cag A N = 11	Vac As1+ Cag A + VacAs2 N = 7	P-value
Chronic inflammation	absent or mild moderate or severe	18 (48.6%) 19 (51.4%)	0 (0%) 11 (100%)	0 (0%) 7 (100%)	0.001٭
Activity	absent or mild moderate or severe	29 (78.4%) 8 (21.6%)	1 (9.1%) 10 (90.9%)	0 (0%) 7 (100%)	< 0.0001٭
Atrophy	Absent Focal	37 (100%) 0 (0%)	7 (63.6%) 4 (36.4%)	7 (100%) 0 (0%)	< 0.0001٭
Intestinal metaplasia	Absent Present	35 (94.6%) 2 (5.4%)	11 (100.0%) 0 (0.0%)	3 (42.9%) 4 (57.1%)	< 0.0001٭
Atypia	Absent Mild atypia	37 (100.0%) 0 (0.0%)	9 (81.8%) 2 (18.2%)	7 (100.0%) 0 (0.0%)	0.016٭

Histopathological changes in response to different H. pylori genes were reported in the above table. Significant differences were documented in different types of genes concerning chronic inflammation, activity, atrophy, intestinal metaplasia, and atypia of gastric mucosa.
*Significant differences

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