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Table 2 Healthcare use of RSV infections in young children in the 14 days after enrollment

From: Pre-COVID-19-pandemic RSV epidemiology and clinical burden in pediatric primary care in Italy: a comparative analysis across two regions for the 2019/2020 season

 

Total

(n = 116)

1–12

months

(n = 52)

13–24 months

(n = 25)

25–60 months

(n = 39)

p*

Lazio

(n = 52)

Apulia

(n = 64)

p*

Healthcare usage$

87 (75%)

45 (87%)

18 (72%)

24 (62%)

0.024

31 (60%)

56 (88%)

0.001

Number of consultation to pediatrician after swab (median, IQR)

1 (0–2)

2 (1–3)

1(0–2)

1 (0–2)

0.094

1 (0–2)

2 (–3)

< 0.001

Number ofphone call/email after swab

1 (0–2)

1 (1–3)

1 (0–2)

1 (0–2)

0.861

1 (0–2)

(1–3)

0.025

Consultation with another doctor (sub-specialist) after swab n (%)

11 (9%)

5 (10%)

1 (4%)

5 (13%)

0.501

5 (10%)

6 (9%)

0.965

Emergency department n (%)

18(16%)

11 (21%)

3 (12%)

4 (10%)

0.314

3 (6%)

15 (23%)

0.009

Hospitalizations n (%)

7 (6%)

6 (12%)

0 (-)

1 (3%)

0.074

2 (4%)

5 (8%)

0.372

Days of hospitalizations (median, IQR)

7 (3–9)

7 (3–9)

-

4 (4–4)

0.611

2.5 (–3)

7 (7–9)

0.049

Use of medications and prophylaxes

        

Paracetamol

47 (43%)

14 (30%)

16 (64%)

17 (44%)

0.024

15 (31%)

32 (52%)

0.021

Other pain medication (e.g. ibuprofen)

4 (4%)

0 (-)

0 (-)

4 (10%)

0.023

2 (4%)

2 (3%)

0.823

Antibiotics

34 (31%)

8 (17%)

10 (40%)

16 (41%)

0.034

15 (31%)

19 (31%)

0.952

Bronchodilators

38 (31.9%)

18 (34%)

10 (38.6%)

10 (25%)

0.160

38 (69.1%)

0

< 0.001

Steroids

6 (5%)

2 (3.8%)

3 (11.5%)

1 (2.5%)

0.120

6 (10.9%)

0

0.009

Cough syrup

4 (3.4%)

0

4 (15.4%)

0

0.001

4 (7.3%)

0

0.034

Use of any medication^

110 (95%)

46 (88%)

25 (100%)

39 (100%)

0.020

49 (94%)

61 (95%)

0.794

Palivizumab n (%)

0 (-)

0 (-)

0 (-)

0 (-)

-

0 (-)

0 (-)

-

  1. *p < 0.05 $ Healthcare usage was defined as at least one of the following variables: consultation to PCP after swab, home visits by PCP, consultation with another doctor after swab, access to emergency department and hospitalizations. ^ Medication included antibiotics, paracetamol, other pain medication (e.g. ibuprofen) and other medication. None of the patients reported home visits, intensive care unit admission, or paramedical care at day 14. These outcomes were not reported in the table.