Table 4 Analysis of the associations between 30-day mortality and vancomycin trough concentration

Ethnicity

1.047

(0.933 ~ 1.174)

0.439

Gender

0.955

(0.803 ~ 1.136)

0.603

Age

1.026

(1.015 ~ 1.038)

 < 0.001

1.035

(1.021 ~ 1.048)

 < 0.001

Myocardial infarction

1.498

(1.152 ~ 1.950)

0.003

0.956

(0.710 ~ 1.288)

0.769

Congestive heart failure

2.001

(1.652 ~ 2.425)

 < 0.001

1.662

(1.310 ~ 2.109)

 < 0.001

Chronic pulmonary disease

1.108

(0.927 ~ 1.324)

0.260

Cerebrovascular disease

1.354

(1.082 ~ 1.694)

0.008

1.579

(1.236 ~ 2.018)

 < 0.001

Hypertension

1.221

(1.017–1.467)

0.033

0.808

(0.634–1.028)

0.083

Diabetes

0.960

(0.802 ~ 1.150)

0.660

Renal disease

1.554

(1.277 ~ 1.892)

 < 0.001

1.012

(0.795 ~ 1.289)

0.920

Malignant cancer

1.486

(1.205 ~ 1.833)

 < 0.001

1.644

(1.300 ~ 2.079)

 < 0.001

Liver disease

2.237

(1.644 ~ 3.044)

 < 0.001

1.299

(0.904 ~ 1.866)

0.157

AIDS

0.540

(0.066 ~ 4.399)

0.565

White blood cell

1.026

(1.015 ~ 1.037)

 < 0.001

1.019

(1.008 ~ 1.031)

0.001

Hemoglobin

0.855

(0.803 ~ 0.910)

 < 0.001

0.962

(0.897 ~ 1.032)

0.276

Platelet

0.998

(0.997 ~ 0.999)

 < 0.001

0.999

(0.998 ~ 1.000)

0.083

Bilirubin

1.152

(1.104 ~ 1.202)

 < 0.001

1.074

(1.026 ~ 1.123)

0.002

Albumin

0.701

(0.590 ~ 0.832)

 < 0.001

0.586

(0.481 ~ 0.714)

 < 0.001

Creatinine

1.329

(1.224 ~ 1.443)

 < 0.001

1.099

(0.990 ~ 1.219)

0.076

Glucose

1.004

(1.002 ~ 1.007)

 < 0.001

1.004

(1.002 ~ 1.007)

 < 0.001

Vancomycin trough concentration

1.033

(1.023 ~ 1.043)

 < 0.001

1.018

(1.006 ~ 1.031)

 < 0.001

GCS

0.917

(0.898 ~ 0.936)

 < 0.001

0.936

(0.913 ~ 0.959)

 < 0.001

Ventilation

0.925

(0.778 ~ 1.099)

0.375

Other nephrotoxic medications

1.461

(1.204–1.773)

 < 0.001

0.111

(0.608 ~ 1.053)

0.800

Shock

2.437

(2.043 ~ 2.908)

 < 0.001

1.147

(0.893 ~ 1.474)

0.282

SOFA

1.170

(1.145 ~ 1.196)

 < 0.001

1.099

(1.062 ~ 1.137)

 < 0.001