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Table 1 Socio-demographic and clinical factors associated with severity of very severe viral acute respiratory infections (VSVARI) among children under five years of age

From: Predictors of severity and prolonged hospital stay of viral acute respiratory infections (ARI) among children under five years in Burkina Faso, 2016–2019

   

Very severe viral acute respiratory infection compared to other SARI cases

Variables

Total sample n (%)

Total N = 1159

Total

VSVARI n (%VSVARI)

Total n = 344

Crude OR

(95% CI)

p-value

Adjusted

OR (95% CI)

p-value

Age group

      

 0–3 months

149 (12.9)

58 (16.9)

1.7 (1.2–2.4)

0.006**

1.5 (1.1–2.3)

0.044*

 4–11 months

357 (30.8)

107 (31.1)

1.1 (0.8–1.5)

0.388

1.1 (0.8–1.5)

0.581

 12–59 months

653 (56.3)

179 (52)

ref

---

1(ref.)

---

Area of residence

      

 Urban

514 (44.3)

166 (48.3)

1.25(1-1.6)

0.082

1.3 (1.1–1.7)

0.034*

 Rural

645 (55.7)

178 (51.7)

1(ref.)

---

1(ref.)

---

Sex

      

 Male

679(58.6)

211(61.3)

1.17(0.9–1.5)

0.217

---

---

 Female

480(41.4)

133(38.7)

1(ref.)

---

---

---

Season***

      

 Dry season

819(70.7)

220(70.7)

1(ref.)

--

1(ref.)

---

 Rainy season

344(29.3)

124(340)

1.6(1,2–2)

0.001**

1.4(1.1–1.9)

0.028*

Sites

      

 Bogodogo

324(28)

73(21.2)

1(ref.)

--

---

---

 Bousse

183(15.8)

49(14.2)

1.25(0.8–1.9)

0.283

---

---

 Kongoussi

341(29.4)

60(17.4)

0.73(0.5–1.1)

0.112

---

---

 Houndé

311(26.8)

162(47.1)

3.7(2.6–5.3)

< 0.001**

---

---

Antibiotics before admission

 No

460(39.7)

148(43)

1(ref.)

--

---

---

 Yes

699(60.3)

196(57)

0.8(0.6–1.1)

0.132

---

---

Antibiotics during hospitalization

 No

19(1.6)

9(2.6)

2.2(0.9–5.4)

0.095

2.7(1.1–7.2)

0.048*

 Yes

1140(98.4)

335(97.4)

1(ref.)

--

1(ref.)

---

Type of antibiotics used

Ceftriaxone

1121 (96.7)

332(29.6)

0.9(0.4–1.8)

0.795

---

---

Penicilline G

12(1.04)

3(25)

0.8(0.2–2.9)

0.722

---

---

Gentamycin

104(9)

32(30.8)

1.1(0.7–1.6)

0.799

---

---

Others antibiotics****

29(2.5)

3(10.34)

0.3(0.1–0.9)

0.031*

---

---

Chronic health condition*****

 No

1147(99)

340(98.8)

1(ref.)

--

---

---

 Yes

12(1)

4(1.2)

1.2(0.3-4)

0.776

---

---

Length of stay

      

 0–7 Days

920(79.4)

278(80.8)

1.1(0.8–1.5)

0.450

---

---

 >7 Days

239(20.6)

66(19.2)

1(ref.)

--

---

---

Malnutrition

      

 No

1072(92.5)

323(93.9)

1.3(0.8–2.2)

0.247

1.6(0.9–2.8)

---

 Yes

87(7.5)

21(6.1)

1(ref.)

--

1(ref.)

---

  1. *p < 0.05 ** p < 0.01; VSVARI : Very severe viral acute respiratory infection ; ***Rainy season : June to September, dry season : October to may [25]; OR : odds ratio
  2. ****others antibiotics: Amoxicillin, metronidazole, ampicillin, cefotaxime; *****Chronic health conditions : asthma, circle cell diseases, HIV, diabetes, obesity, epilepsy, high blood pressure