Table 2 Patient’s characteristics and prognosis difference in the clusters of discovery cohort
Cluster 1 (n = 211) | Cluster 2 (n = 149) | P value | |
|---|---|---|---|
Demographic characteristics | |||
Age, years | 64.00 [51.00, 73.00] | 64.00 [50.00, 75.00] | 0.450 |
Gender, female | 89 (42.2) | 45 (30.2) | 0.027 |
BMI | 22.49 [20.03, 25.37] | 23.04 [19.95, 25.39] | 0.837 |
From which department transfer to ICU | < 0.001 | ||
Direct transfer from ED | 136 (64.5) | 41 (27.5) | |
Emergency room | 13 (6.2) | 10 (6.7) | |
Surgical department | 54 (25.6) | 78 (52.3) | |
Internal-medicine department | 8 (3.8) | 20 (13.4) | |
SOFA | 6.00 [4.00, 9.50] | 9.00 [6.00, 12.00] | < 0.001 |
Pitt bacteremia Score | 2.00 [0.00, 5.00] | 5.00 [3.00, 6.00] | < 0.001 |
Pre-existing conditions | |||
Cardiovascular disease | 21 (10.0) | 18 (12.1) | 0.640 |
Cerebrovascular disease | 18 (8.5) | 16 (10.7) | 0.601 |
Diabetes | 56 (26.5) | 26 (17.4) | 0.058 |
Tumor | 27 (12.8) | 36 (24.2) | 0.008 |
Chronic kidney diseases | 10 (4.7) | 5 (3.4) | 0.704 |
Autoimmune disease | 11 (5.2) | 6 (4.0) | 0.787 |
Before bloodstream infection | |||
hospital stays, days | 0.00 [0.00, 4.00] | 13.00 [6.00, 21.00] | < 0.001 |
ICU stays, days | 0.00 [0.00, 1.00] | 7.00 [1.00, 12.00] | < 0.001 |
Surgical operation | 58 (27.5) | 96 (64.4) | < 0.001 |
Mechanical ventilation | 16 (7.6) | 117 (78.5) | < 0.001 |
Deep vein catheterization | 38 (18.0) | 133 (89.3) | < 0.001 |
Antibiotic use | 78 (37.0) | 145 (97.3) | < 0.001 |
vasopressors use | 5 (2.4) | 105 (70.5) | < 0.001 |
ICU complication | |||
MODS | 58 (27.5) | 70 (47.0) | < 0.001 |
ARDS | 71 (33.6) | 93 (62.4) | < 0.001 |
Septic shock | 69 (32.7) | 72 (48.3) | 0.004 |
AKI | 61 (28.9) | 51 (34.2) | 0.338 |
DIC | 23 (10.9) | 16 (10.7) | 1.000 |
Outcomes | |||
hospital stays, days | 15.00 [10.00, 27.00] | 32.00 [21.00, 49.00] | < 0.001 |
ICU stays, days | 11.00 [7.00, 18.50] | 18.00 [9.00, 33.00] | < 0.001 |
ICU mortality | 36 (17.1) | 62 (41.6) | < 0.001 |