Table 2 Analysis of osteoporosis indices [n(%), x ̅±s, M(P25,P75)]
From: H. pylori infection and osteoporosis: a large-scale observational and mendelian randomization study
Project | Normal bone mass group(298) | Low bone mass group(295) | Osteoporosis group(307) | F/χ2 /H | rs | P |
|---|---|---|---|---|---|---|
Sex(Male/Female) | 141(45.19)/157(26.70) | 123(39.42)/172(29.25) | 48(15.38)/259(44.05) | 76.579 | - | <0.001 |
Age (years) | 48.44 ± 17.48 | 55.68 ± 16.28 | 64.62 ± 15.49 | 73.732 | 0.374 | <0.001 |
SBP(mmHg) | 121(112,133) | 128(117,140) | 130(120,140) | 29.828 | 0.181 | <0.001 |
H. pylori(positive/Negative) | 59(12.55)/239(55.58) | 158(33.62)/137(31.86) | 253(53.83)/54(12.56) | 237.905 | - | <0.001 |
FPG(mmol/L) | 4.99(4.61,5.44) | 4.98(4.65,5.45) | 5.08(4.71,6.07) | 7.598 | 0.081 | 0.022 |
DBP(mmHg) | 75(68,83) | 79(70,86) | 78(70,87) | 8.448 | 0.086 | 0.015 |
BMI(kg/m 2) | 24.10(21.50,26.67) | 23.90(21.70,26.20) | 22.00(19.90,25.30) | 45.779 | -0.202 | <0.001 |
WBC(*109/L) | 5.86(4.86,7.10) | 5.72(4.79,6.84) | 5.75(4.69,6.82) | 1.896 | - | 0.387 |
NEU (%) | 57.05(51.98,61.83) | 56.80(50.50,62.80) | 56.90(50.00,65.40) | 1.665 | - | 0.435 |
LYM (%) | 33.80(28.60,39.03) | 34.20(28.60,39.60) | 32.70(23.70,39.60) | 6.356 | -0.067 | 0.042 |
CA(mmol/L) | 2.29(2.19,2.40) | 2.26(2.19,2.37) | 2.27(2.20,2.37) | 0.437 | - | 0.804 |
P(mmol/L) | 1.06(0.92,1.19) | 1.11(0.99,1.19) | 1.09(1.01,1.22) | 2.427 | - | 0.297 |
MG(mmol/L) | 0.89(0.84,0.96) | 0.90(0.85,0.95) | 0.91(0.84,0.97) | 0.536 | - | 0.765 |
ALP(U/L) | 64.90(52.00,84.00) | 72.00(54.00,90.90) | 74.00(58.50,95.00) | 6.891 | 0.126 | 0.032 |
ALB(g/L) | 49.00(43.00,52.80) | 44.90(38.90,50.00) | 39.50(36.50,44.80) | 144.398 | -0.400 | <0.001 |
TP(g/L) | 72.51(67.03,77.12) | 69.45(64.99,74.30) | 65.18(59.90,70.30) | 116.203 | -0.356 | <0.001 |
TC(mmol/L) | 4.43(3.79,5.03) | 4.45(3.83,5.14) | 4.46(3.78,5.22) | 0.859 | - | 0.651 |
TG(mmol/L) | 1.35(0.90,2.20) | 1.49(1.05,2.12) | 1.22(0.93,1.73) | 14.541 | -0.073 | 0.001 |
HDL-C(mmol/L) | 1.35(1.11,1.63) | 1.25(1.04,1.44) | 1.17(0.99,1.39) | 35.117 | -0.195 | <0.001 |
LDL-C(mmol/L) | 2.11(1.56,2.57) | 2.35(1.79,2.92) | 2.31(1.91,2.92) | 26.001 | 0.152 | <0.001 |
SCr(umol/L) | 62.98(53.58,73.32) | 62.98(52.64,73.00) | 59.00(51.00,69.00) | 9.404 | -0.093 | 0.009 |
UA(umol/L) | 315.13(267.93,396.80) | 295.85(248.00,359.87) | 253.00(212.00,307.00) | 95.513 | -0.319 | <0.001 |
hs-CRP(mg/L) | 1.70(0.57,5.33) | 2.30(0.80,9.80) | 3.40(1.33,11.45) | 12.403 | 0.173 | 0.002 |
VitD(ng/ml) | 19.88(35.36,12.75) | 13.87(8.81,19.67) | 12.62(7.46,18.99) | 26.351 | -0.230 | <0.001 |
PTH(pg/ml) | 54.60(43.18,78.03) | 52.20(40.30,77.10) | 48.80(35.55,72.00) | 4.515 | - | 0.105 |
OC(ng/ml) | 13.81(9.37,19.13) | 16.76(12.33,24.97) | 18.73(13.57,26.27) | 16.329 | 0.184 | <0.001 |