Table1 Causal effects of gut microbiome on HIV infection

Actinobacteria

genus

Eggerthella

IVW

10

-0.740

0.267

0.477

0.283

0.805

0.006

0.089

2.071

0.979

-0.245

0.135

0.106

Firmicutes

class

Erysipelotrichia

IVW

13

-1.280

0.493

0.278

0.106

0.731

0.009

0.232

13.602

0.256

-0.157

0.127

0.244

Firmicutes

class

Weighted median

-1.825

0.648

0.161

0.045

0.575

0.005

0.245

Firmicutes

family

Defluviitaleaceae

IVW

11

-0.681

0.321

0.506

0.270

0.948

0.034

0.423

6.600

0.679

0.125

0.112

0.291

Firmicutes

family

Erysipelotrichaceae

IVW

13

-1.280

0.493

0.278

0.106

0.731

0.009

0.232

13.602

0.256

-0.157

0.127

0.244

Firmicutes

family

Weighted median

-1.825

0.616

0.161

0.048

0.539

0.003

0.168

Firmicutes

family

Ruminococcaceae

IVW

9

0.903

0.440

2.468

1.043

5.842

0.040

0.452

4.266

0.749

-0.121

0.094

0.242

Firmicutes

family

Weighted median

1.214

0.597

3.365

1.045

10.836

0.042

0.736

Firmicutes

genus

Anaerotruncus

IVW

13

-0.836

0.402

0.434

0.197

0.954

0.038

0.439

8.052

0.709

-0.068

0.080

0.415

Firmicutes

genus

Weighted median

-1.080

0.535

0.340

0.119

0.970

0.044

0.744

Firmicutes

genus

Clostridium

IVW

7

-0.857

0.431

0.424

0.182

0.988

0.047

0.492

5.442

0.364

-0.023

0.115

0.850

Firmicutes

genus

Coprococcus2

IVW

8

-0.976

0.441

0.377

0.159

0.894

0.027

0.391

5.093

0.532

-0.141

0.249

0.591

Firmicutes

genus

Fusicatenibacter

IVW

18

-0.374

0.385

0.688

0.323

1.465

0.332

0.873

14.826

0.537

0.201

0.090

0.040

Firmicutes

genus

MR Egger

-3.254

1.338

0.039

0.003

0.531

0.027

1.000

Firmicutes

genus

Ruminococcaceae UCG005

IVW

14

0.718

0.342

2.051

1.048

4.011

0.036

0.432

11.441

0.492

-0.021

0.078

0.797

Firmicutes

genus

Subdoligranulum

IVW

11

1.375

0.413

3.957

1.762

8.887

0.001

0.085

8.564

0.478

-0.043

0.078

0.592

Firmicutes

genus

Weighted median

1.455

0.580

4.286

1.376

13.354

0.012

0.445

Firmicutes

order

Bacillales

IVW

9

-0.494

0.213

0.610

0.402

0.927

0.021

0.352

5.687

0.577

0.026

0.138

0.855

Firmicutes

order

Erysipelotrichales

IVW

13

-1.280

0.493

0.278

0.106

0.731

0.009

0.232

13.602

0.256

-0.157

0.127

0.244

Firmicutes

order

Weighted median

-1.825

0.607

0.161

0.049

0.530

0.003

0.168

Lentisphaerae

genus

Victivallis

IVW

10

0.473

0.235

1.605

1.012

2.547

0.044

1.000

9.228

0.323

0.255

0.231

0.302

Methanomada

genus

Methanobrevibacter

IVW

6

-0.675

0.334

0.509

0.265

0.980

0.043

1.000

6.052

0.195

-0.028

0.200

0.895