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Table 4 Association between selected factors and latent as well as incubation periods using multivariate AFT model

From: Latent and incubation periods of Delta, BA.1, and BA.2 variant cases and associated factors: a cross-sectional study in China

 

Latent period

 

Incubation period

Delta (672)

 

Omicron (885)

 

Delta (405)

 

Omicron (420)

exp (\( \varvec{\beta }\)) (95%CI)

p value

 

exp (\( \varvec{\beta }\)) (95%CI)

p value

 

exp (\( \varvec{\beta }\)) (95%CI)

p value

 

exp (\( \varvec{\beta }\)) (95%CI)

p value

Sex

           

Male

1 (ref)

··

 

1 (ref)

··

 

1 (ref)

··

 

1 (ref)

··

Female

1.01 (0.91 ~ 1.13)

0.839

 

0.95 (0.87 ~ 1.05)

0.334

 

0.99 (0.88 ~ 1.11)

0.887

 

0.97 (0.88 ~ 1.07)

0.546

Age

           

0 ~ 17

1 (ref)

··

 

1 (ref)

··

 

1 (ref)

··

 

1 (ref)

··

18 ~ 49

0.81 (0.66 ~ 0.98)

0.034

 

0.82 (0.71 ~ 0.94)

0.004

 

0.69 (0.55 ~ 0.86)

< 0.001

 

0.83 (0.72 ~ 0.96)

0.013

50~

1.04 (0.87 ~ 1.25)

0.669

 

1.07 (0.92 ~ 1.26)

0.373

 

0.89 (0.71 ~ 1.10)

0.270

 

0.95 (0.80 ~ 1.14)

0.593

Vaccination history

           

Unvaccinated

1 (ref)

··

 

1 (ref)

··

 

1 (ref)

··

 

1 (ref)

··

Partially vaccinated

0.97 (0.85 ~ 1.11)

0.676

 

1.05 (0.78 ~ 1.41)

0.757

 

0.96 (0.84 ~ 1.11)

0.606

 

0.98 (0.75 ~ 1.27)

0.856

Fully vaccinated

0.98 (0.85 ~ 1.13)

0.789

 

1.07 (0.88 ~ 1.28)

0.501

 

1.00 (0.86 ~ 1.16)

0.962

 

1.03 (0.86 ~ 1.23)

0.751

Booster

··

··

 

0.97 (0.81 ~ 1.17)

0.780

 

··

··

 

1.02 (0.85 ~ 1.21)

0.864

Clinical severity

           

Asymptomatic

1 (ref)

··

 

1 (ref)

··

 

NA

NA

 

NA

NA

Mild

1.35 (0.90 ~ 2.04)

0.148

 

1.00 (0.89 ~ 1.13)

0.969

 

1 (ref)

··

 

1 (ref)

··

Moderate/Severe/Critical

1.23 (0.83 ~ 1.83)

0.304

 

0.99 (0.84 ~ 1.17)

0.914

 

1.02 (0.86 ~ 1.20)

0.864

 

1.07 (0.91 ~ 1.26)

0.395

Number of infectors

           

> 1

1 (ref)

··

 

1 (ref)

··

 

1 (ref)

··

 

1 (ref)

··

= 1

0.92 (0.81 ~ 1.04)

0.190

 

0.96 (0.87 ~ 1.05)

0.378

 

0.90 (0.79 ~ 1.03)

0.133

 

0.99 (0.90 ~ 1.10)

0.904

Exposure window

           

≤ 3 days

1 (ref)

··

 

1 (ref)

··

 

1 (ref)

··

 

1 (ref)

··

> 3 days

1.06 (0.94 ~ 1.19)

0.359

 

1.51 (1.35 ~ 1.70)

< 0.001

 

1.05 (0.92 ~ 1.19)

0.469

 

1.48 (1.32 ~ 1.66)

< 0.001

Shedding window

           

≤ 3 days

1 (ref)

··

 

1 (ref)

··

 

1 (ref)

··

 

1 (ref)

··

> 3 days

0.80 (0.70 ~ 0.90)

< 0.001

 

0.85 (0.71 ~ 1.02)

0.081

 

0.96 (0.86 ~ 1.07)

0.469

 

1.21 (1.08 ~ 1.36)

0.001

Omicron sublineages

           

BA.1

NA

NA

 

1 (ref)

··

 

NA

NA

 

1 (ref)

··

BA.2

NA

NA

 

0.99 (0.88 ~ 1.12)

0.886

 

NA

NA

 

1.03 (0.90 ~ 1.18)

0.648

  1. Notes NA represented that the figure was not applicable for this cell