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Table 2 Baseline characteristics of the study population

From: Persistent high sepsis-induced coagulopathy and sequential organ failure assessment scores can predict the 28-day mortality of patients with sepsis: A prospective study

Characteristic

Overall

(n = 209)

Survivors

(n = 131)

Non-survivors

(n = 78)

P-value

Age (years), median (IQR)

83 (74, 88)

81 (70, 88)

85 (80, 90)

0.002

Male, n (%)

126 (60.3%)

83 (63.4)

43 (55.1)

0.240

BMI (kg/m2), mean ± SD

21.73 ± 4.31

22.18 ± 4.20

20.99 ± 4.41

0.053

Comorbidities, n (%)

    

Hypertension

126 (60.3%)

78 (59.5%)

48 (61.5%)

0.775

Diabetes mellitus

91 (43.5%)

54 (41.2%)

37 (47.4%)

0.381

Cardiovascular disease

66 (31.6%)

40 (30.5%)

26 (33.3%)

0.674

Cerebrovascular disease

62 (29.7%)

38 (29.0%)

24 (30.8%)

0.787

Chronic kidney disease

13 (6.2%)

7 (5.3%)

6 (7.7%)

0.701

Site of infection, n (%)

    

Lung

165 (78.9%)

99 (75.6%)

66 (84.6%)

0.121

Abdomen

46 (22.0%)

32 (24.4%)

14 (17.9)

0.274

Urinary tract

51 (24.4%)

32 (24.4%)

19 (24.4%)

0.991

Soft tissue

11 (5.3%)

4 (3.1%)

7 (9.0%)

0.125

Laboratory values

    

WBC (×109/L), median (IQR)

13.27 (9.29, 19.45)

13.10 (8.90, 18.55)

13.91 (9.92, 20.22)

0.414

CRP (mg/L), median (IQR)

99.69 (30.07, 207.08)

103.40 (23.80, 220.00)

82.24 (39.82, 186.92)

0.714

IL-6 (pg/mL), median (IQR)

102.90 (35.90, 466.70)

92.00 (34.20, 339.10)

128.70 (39.50, 508.35)

0.333

Platelet (×109/L), median (IQR)

167.00 (110.00, 249.00)

165.00 (112.00, 243.00)

174.00 (108.00, 250.25)

0.725

PT (s), median (IQR)

13.20 (12.30, 14.20)

13.00 (12.30, 14.10)

13.35 (12.20, 15.00)

0.126

INR, median (IQR)

1.16 (1.07, 1.25)

1.14 (1.07, 1.24)

1.19 (1.06, 1.33)

0.111

APTT (s), median (IQR)

34.20 (28.60, 42.40)

33.40 (28.60, 41.70)

35.20 (28.53, 43.60)

0.497

Fibrinogen (g/L), median (IQR)

4.52 (3.23, 5.46)

4.81 (3.27, 5.46)

4.06 (2.94, 5.31)

0.089

D-dimer (mg/L), median (IQR)

2.74 (1.34, 6.28)

2.27 (1.17, 5.13)

4.24 (1.75, 7.88)

0.006

Albumin (g/L), mean ± SD

33.94 ± 6.18

34.96 ± 6.09

32.22 ± 6.00

0.002

Creatinine (umol/L), median (IQR)

137.00 (93.35, 208.50)

131.00 (89.00, 192.00)

175.90 (100.78, 239.75)

0.050

Lactate (mmol/L), median (IQR)

2.52 (1.45, 4.40)

2.20 (1.30, 4.26)

3.01 (1.85, 5.88)

0.009

APACHE II score, median (IQR)

24.00 (19.00, 28.00)

21.00 (17.00, 27.00)

27.00 (22.75, 33.00)

< 0.001

Septic shock, n (%)

69 (33.0%)

34 (26.0%)

35 (44.9%)

0.005

Length of stay (days), median (IQR)

13.00 (8.00, 24.00)

17.00(10.00, 32.00)

7.50 (3.00, 15.25)

< 0.001

  1. BMI: body mass index; WBC: white blood cell; CRP: C-reactive protein; IL-6: interleukin-6; PT: prothrombin time; INR: international normalized ratio; APTT: activated partial thromboplastin time; APACHE II: Acute Physiology and Chronic Health Evaluation II; IQR: interquartile range; SD: standard deviation
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BMC Infectious Diseases

ISSN: 1471-2334

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