Fig. 1

Positions of primer attachment sites and areas corresponding to each of the PCR amplicons, as well as the most specific mutations identified in the RdRp gene among the SARS-CoV-2 samples isolated from COVID-19 patients in relation to the sequence encoding the RdRp enzyme in the genome of the SARS-CoV-2 virus. Legend: Mutations shown in blue-green were identified only in viruses collected from the severe illness study group. The mutation shown in red was identified only in viruses collected from the symptomless study group. The mutation shown in purple was identified in both groups. The conserved domains identified by a Conserved Domain Search tool are shown as green boxes underneath the black line representing the sequence. The blue numbers above the black line are nucleotide positions, concordant with the SARS-CoV-2 reference sequence (NC_045512.2). The figure was prepared using (https://inkscape.org/) 1.3 software