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Table 2 Brief summarization of included patients

From: Diagnosis of pulmonary Scedosporium apiospermum infection from bronchoalveolar lavage fluid by metagenomic next-generation sequencing in an immunocompetent female patient with normal lung structure: a case report and literature review

Characteristics

25 patients

Sex (male / female)

13/12

Median age (year)

55 (7–83)

Underlying disease

21 (0.84)

Pulmonary tuberculosis

11 (0.44)

Pulmonary cystic fibrosis

4 (0.16)

Bronchiectasis

3 (0.12)

Previous diagnosis of S. apiospermum

1 (0.04)

Pulmonary arterial hypertension

1 (0.04)

Diabetes

1 (0.04)

Previous tumor history

1 (0.04)

Oral abscess

1 (0.04)

No underlying disease

4 (0.16)

Clinical manifestations

    Cough, Expectoration

16 (0.64)

    Hemoptysis

12 (0.48)

    Fever

10 (0.40)

    Dyspnea

9 (0.36)

    Night sweats

3 (0.12)

    Blood in sputum

2 (0.08)

    Weight loss

3 (0.12)

    Loss of appetite

2 (0.08)

    Chest pain

2 (0.08)

    Fatigue

2 (0.08)

    Pneumothorax

1 (0.04)

Diagnosis time

    Misdiagnosed

9 (0.36)

    No misdiagnosis

16 (0.64)

Diagnostic methods

    BALF culture

13 (0.52)

    Sputum culture

7 (0.28)

    Blood culture

1 (0.04)

    Lung biopsy tissue smear

1 (0.04)

    Lung biopsy tissue specimen culture

2 (0.08)

    Postoperative tissue culture

4 (0.16)

    DNA/RNA sequencing of BALF

2 (0.08)

Lesion range

    Limited

12 (0.48)

    Extensive

13 (0.52)

Treatment scheme

    Antifungal therapy

15 (0.60)

    Surgery treatment

4 (0.16)

    Antifungal + Surgery

6 (0.24)

Prognosis

    Cure

19 (0.76)

    Improvement

2 (0.08)

    Death

2 (0.08)

    No mention

2 (0.08)