Outbreak investigation of Serratia marcescens bloodstream infection in an obstetric ward for high-risk pregnant women

Table 1 Clinical outcomes of the patients with S. marcescens blood stream infection

	Patient A	Patient B	Patient C	Patient D
Age (years)	27	34	38	35
GA at the admission (weeks + days)	27 + 1	21 + 2 (twin)	33 + 5	29 + 4 (twin)
Major diagnosis	Preterm labor	IIOC and Preterm labor	Preeclampsia	TTTS and Preterm labor
Treatment before BSI	Tocolytics (Atosiban + magnesium)	Tocolytics (Ritodrine + magnesium)	Tocolytics (magnesium)	Tocolytics (Ritodrine + Atosiban + magnesium)
Start date of BSI during hospitalization	HD 5	HD 13	HD 21	HD 8
Length of stay in the unit (days)	25	21	29	17
Symptom of BSI	Fever	Fever	Fever	Fever
Prognosis of patients	Unknown^a	Recovery	Recovery	Recovery
Prognosis of fetus	Unknown^a	No evidence of S. marcescens infection	No evidence of S. marcescens infection	No evidence of S. marcescens infection
Preterm birth (GA, weeks + days)	Unknown^a	Yes (36 + 1)	Yes (36 + 5)	Yes (31 + 3)
Association between BSI and preterm birth	N/A	No	Yes^b	Unknown^c
Transmission of S. marcescens	No	No	No	No

Abbreviations: IIOC Incompetent internal os of cervis, TTTS Twin to twin transfusion syndrome, BSI blood stream infection, HD hospital day, GA gestational age, ICT immunochromatography-based rapid diagnostic tests
^aPatient A was transferred to another hospital; thus, her obstetric outcomes could not be identified
^bPatient C underwent an emergency cesarean section the day after developing S. marcescens BSI. After the onset of fever, the surgery was performed due to the aggravation of preeclampsia, and it is considered to be related
^cAfter resolving bacteremia, patient D underwent an emergency cesarean section due to symptomes like uterine contractions and leaking amniotic fluid

ISSN: 1471-2334