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Table 1 Demographic Characteristics and serum aminotransferase levels for HEV infection in 352 people with acute jaundice

From: Hepatitis E outbreak in the health district of Bocaranga-Koui, Central African Republic, 2018–2019

 

IgM anti-HEV

IgG anti-HEV

Characteristics

Positive, No. (%)

Negative, No. (%)

OR (95% CI)

P

Positive, No. (%)

Negative, No. (%)

OR (95% CI)

P

Prevalence

142 (40.3)

204 (57.9)

  

175 (49.7)

163 (46.3)

  

Sex

0.39

 

0.65

 Male

70 (38.9)

110 (61.1)

  

87 (50.6)

85 (49.4)

  

 Female

72 (43.3)

94 (56.7)

  

88 (53.0)

78 (47.0)

  

Age group

0.001

 

0.001

 0–10

16 (14.9)

91 (85.1)

-

 

18 (17.9)

83 (82.1)

-

 

 11–20

27 (42.1)

37 (57.9)

4.1 (2.0–8.6)

0.001

37 (56.0)

29 (44.0)

5.8 (2.9–11.8)

0.001

 21–30

42 (59.1)

29 (40.9)

8.3 (4.0–16.9)

0.001

51 (71.9)

20 (28.1)

11.7 (5.6–24.3)

0.001

 31–40

25 (49.0)

26 (51.0)

5.5 (2.5–11.8)

0.001

31 (63.2)

18 (36.8)

7.9 (3.6–17.1)

0.001

 > 40

32 (61.5)

20 (38.5)

9.2 (4.2–19.8)

0.001

38 (74.5)

13 (25.5)

13.4 (5.9–30.3)

0.001

ASTa, IU/L

0.001

 

0.19

 < 15

2 (18.1)

9 (67.0)

0.5(0.1–2.5)

0.40

2(22.2)

7(77.7)

 

0.90

 15–46

28 (30.4)

64(72.4)

-

 

49(53.8)

42(46.1)

  

 > 46

112 (46.0)

131(50.0)

1.9(1.1–3.2)

0.01

124(52.1)

114(47.9)

 

0.91

ALTb, IU/L

0.001

 

0.001

 < 11

7 (25)

21 (75)

1.0 (0.4–2.7)

0.41

09(36)

16(64)

0.7(0.3–1.7)

0.49

 11–66

41 (23.7)

132 (76.3)

-

 

73 (43.2)

96(56.8)

-

 

 > 66

94 (64.8)

51 (35.1)

5.9 (3.6–9.7)

0.001

93(64.5)

51(35.4)

2.3(1.5–3.7)

0.001

  1. Abbreviations: CI Confidence Interval, HEV hepatitis E virus, OR odds ratio
  2. aAST, aspartateaminotransferase, Normal range: 15–46 IU/L
  3. bALT, alanine aminotransferase, Normal range: 11–66 IU/L