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Table 2 Baseline characteristics for HIV + patients admitted at KNRH (March 2020– March 2023)

From: Mortality and associated factors among people living with HIV admitted at a tertiary-care hospital in Uganda: a cross-sectional study

Variable

Discharged

(N = 4,303)

Died

(N = 1,524)

Total

(N = 5,827)

p value

Median Age (IQR)

39(31–48)

40(31–50)

39 (31–49)

 

Age group (years) (%)

    

 <24

333 (7.74)

101 (6.63)

434 (7.45)

0.053

 25–49

2,976 (69.16)

1,029 (67.52)

4,005 (68.73)

 

 ≥50

994 (23.10)

394 (25.85)

1,388 (23.82)

 

Sex

    

 Female

2,483 (57.70)

810 (53.15)

3,293 (56.51)

0.002

 Male

1,820 (42.30)

714 (46.85)

2,534 (43.49)

 

Address

    

 Distance < 10 km from the hospital

1,720 (39.97)

550 (36.09)

2,270 (38.96)

0.001

 Distance 10-20 km from the hospital

1,550 (36.02)

537 (35.24)

2,087 (35.82)

 

 Distance > 20 km from the hospital

1,033 (24.01)

437 (28.67)

1,470 (25.23)

 

Admission status

    

 New admission

3,790 (88.08)

1,390 (91.21)

5,180 (88.90)

0.001

 Readmission

513 (11.92)

134 (8.79)

647 (11.1)

 

ART Status at Admission

    

 Active on ART

2,824 (65.63)

886 (58.14)

3,710 (63.67)

< 0.001

 ART Naïve

717 (16.66)

256 (16.80)

973 (16.70)

 

 ART Interruption

762 (17.71)

382 (25.07)

1,144 (19.63)

 

Median Days of Hospital Stay (IQR)

6 (3–11)

3 (1–7)

5 (2–10)

 

Median Viral Load (n = 216)

50 (0–13,900)

95(0-119,000)

50(0–28,290)

 

Median CD4 cell count (µL, IQR)

133 (30–380)

57 (16–197)

109 (25–343)

 

CD4 + cell counts

    

 CD4 + ≤ 200 cells/µL

1,624 (37.74)

647 (42.45)

2,271 (38.97)

< 0.001

 CD4 + > 201 cells/µL

1,189 (27.63)

255 (16.73)

1,444 (24.78)

 

 CD4 + Not Documented

1,490 (34.63)

622 (40.81)

2,112 (36.25)

 

Function Assessment

    

 ECOG Score 1–2

3,175 (73.79)

427 (28.02)

3,602 (61.82)

< 0.001

 ECOG Score 3–4

1,128 (26.21)

1,097 (71.98)

2,225 (38.18)

 

Clinical Diagnoses

    

 Tuberculosis

1,429 (33.21)

525 (34.45)

1,954 (33.53)

0.378

 Co-infections

910 (21.15)

457 (29.99)

1,367 (23.46)

< 0.001

 Cardiovascular disease

757 (17.59)

218 (14.30)

975 (16.73)

0.003

 Malnutrition

475 (11.04)

332 (21.78)

807 (13.85)

< 0.001

 Cryptococcal Disease

558 (12.97)

181 (11.88)

739 (12.68)

0.271

 Anaemia

454 (10.55)

192 (12.60)

646 (11.09)

0.029

 Kidney Disease

338 (7.85)

176 (11.55)

514 (8.82)

< 0.001

 Candidiasis

331 (7.69)

112 (7.35)

443 (7.60)

0.664

 Diabetes Mellitus

304 (7.06)

86 (5.64)

390 (6.69)

0.057

 Liver Disease

214 (4.97)

124 (8.14)

338 (5.80)

< 0.001

 Neurologic disorders

191 (4.44)

38 (2.49)

229 (3.93)

0.001

 Chronic Lung Disease

148 (4.04)

37 (2.86)

185 (3.73)

0.053

 COVID-19

114 (2.65)

77 (5.05)

191 (3.28)

< 0.001

 Cancer

108 (2.51)

39 (2.56)

147 (2.52)

0.916

 Toxoplasmosis

102 (2.37)

40 (2.62)

142 (2.44)

0.580

 Kaposi Sarcoma

91 (2.11)

33 (2.17)

124 (2.13)

0.906

  1. ART - Antiretroviral therapy; ECOG - Eastern Cooperative Oncology Group; IQR– Inter quartile range; KNRH– Kiruddu National Referral Hospital