Skip to main content

Table 1 Clinical and immunological characteristics, treatment, SARS-CoV-2 infection, and psychosocial care at each of the check-ups

From: Follow-up for 3 years of a pediatric population diagnosed in 2018 with mother-to-child transmission of HIV in 8 Latin American countries in the PLANTAIDS cohort

 

Check-up 1

(diagnosis – 6 m)

Check-up 2

(7 m – 12 m)

Check-up 3

(13 m – 24 m)

Check-up 4

(25 m – 36 m)

Age (years)

Median (IQR)

3 (1.1–6.05)

3.75 (1.80–8.08)

4.95 (2.73–9.03)

5.95 (4.20–9.08)

ART

68/69 (98.55%)

65/65 (100%)

64/64 (100%)

61/61 (100%)

Good adherence

57/67 (85.07%)

52/61 (85.25%)

53/64 (82.81%)

55/60 (91.67%)

CD4 (cells/µl)

Median (IQR)

875 (540–1338)

1084 (763–1492.5)

985 (696–1259)

1102 (821.5–1371.25)

Viral load < 50 copies/ml

20/68 (29.41%)

34/59 (57.63%)

40/61 (65.57%)

44/59 (74.57%)

Opportunistic infections

28/72 (29.17%)

8/65 (12.31%)

4/61 (6.56%)

4/62 (6.45%)

SARS-CoV-2 infection

0/43 (0%)

0/62 (0%)

0/41 (0%)

3/43 (6.98%)

Clinical stage Na

9/71 (12.67%)

7/63 (11.11%)

7/64 (10.94%)

7/58 (12.07%)

Clinical stage Aa

16/71 (22.53%)

16/63 (25.40%)

18/64 (28.13%)

17/58 (29.31%)

Clinical stage Ba

12/71 (16.90%)

11/63 (17.46%)

9/64 (14.06%)

8/58 (13.79%)

Clinical stage Ca

34/71 (47.89%)

29/63 (46.03%)

30/64 (46.88%)

26/58 (44.83%)

Immunological stage 1

36/64 (56.25%)

41/59 (69.49%)

42/57 (73.68%)

46/56 (82.14%)

Immunological stage 2

17/64 (26.56%)

16/59 (27.12%)

11/57 (19,30%)

8/56 (14.29%)

Immunological stage 3

11/64 (17.19%)

2/59 (3.39%)

4/57 (7.12%)

2/56 (3.57%)

P < 3 weight¥

13/46 (28.26%)

3/38 (7.89%)

2/30 (6.67%)

3/24 (12.5%)

P > 97 weight¥

1/46 (2.17%)

1/38 (2.63%)

0/30 (0%)

0/24 (0%)

P < 3 height¥

23/45 (51.11%)

16/38 (42.11%)

9/30 (30%)

8/24 (33.33%)

P > 97 height¥

0/45 (0%)

0/38 (0%)

0/30 (0%)

0/24 (0%)

BMI

Median (IQR)¥

15.70

(15.09–16.90)

16.19

(14.95–17.72)

16.29

(14.48–17.21)

16.30

(15.31–17.41)

P < 3 BMI§

1/21 (4.17%)

1/24 (4.17%)

1/31 (3.23%)

1/36 (2.78%)

P > 85 BMI§

2/21 (8.33%)

4/24 (16.67%)

4/31 (12.90%)

3/36 (8.33%)

Pathological psychomotor development

12/69 (17.39%)

10/65 (15.38%)

9/64 (14.06%)

5/61 (8.20%)

Correct vaccination

36/53 (67.92%)

33/47 (70.21%)

34/44 (77.27%)

33/41 (80.49%)

COVID-19 vaccine

1/36 (2.78%)

0/30 (0%)

3/35 (8.57%)

5/35 (14.29%)

COVID-19 vaccine type

Comirnaty (Pfizer-BioNTech)

 

2 × Comirnaty (Pfizer-BioNTech)

CoronoVac (Sinovac Biotech)

3 × Comirnaty (Pfizer-BioNTech)

2 × CoronoVac (Sinovac Biotech)

  1. ART Antiretroviral treatment, P Percentile, BMI Body mass index
  2. ¥Only in children under 5 years
  3. §Only in children over 5 years
  4. aAccording to the CDC clinical classification