Fig. 2

Associations between pre-ART clinical and laboratory characteristics with subsequent paradoxical TB-IRIS events. The variables that showed a significant relationship with the development of paradoxical TB-IRIS (from Table 1), that is, age, haemoglobin, baseline CD4 + T-cell counts, HIV VL, and miliary were included in this predictive model. Association of all variables with risk for TB-IRIS was assessed in adjusted logistic regression models. Odds ratios for values below or above threshold levels were displayed in a forest plot R—odds ratio; CI—confidence level