Fig. 2

Association between SARS-CoV-2 infection and conditions in 31 to 150 days after SARS-CoV-2 testing. Notes: Associations were assessed using Cox proportional hazard regression models, accounting for time from the beginning of the post-acute period (31 days post) to the earliest presence of the first diagnostic code for each condition (event) and the end of the outcome period (150 days post-censoring). The overall hazard ratios were calculated using meta-analyses from site-specific estimates. Mental health conditions include anxiety, depression, other mood disorders, overdose, psychosis, substance misuse, and suicide ideation/attempts. Chronic kidney disorders include chronic kidney disease and nephrotic and nephritic syndromes. Hematologic disorders include other venous thromboembolism and pulmonary embolism. Major adverse cardiovascular events include arrythmias heart failure, intracerebral hemorrhage, ischemic infarction, myocardial infarction, myocarditis, subarachnoid hemorrhage, transient ischemic attack or other stroke. Neurological disorders include ataxia, autonomic dysfunction, dementia, encephalitis, myoneural disorders, parkinsonism, peripheral nerve disorders, and seizures. Respiratory disease includes asthma, chronic bronchitis, chronic obstructive pulmonary disease, hypoxemia, interstitial lung disease, pulmonary edema, pulmonary hypertension, and chronic respiratory failure. For both children and adults, regressions were adjusted for age, age squared, sex, race, ethnicity, weight class, number of encounters in the health systems. For adults, we additionally adjusted for combined comorbidity score based on the baseline health conditions and current smoking status. For hospitalized children and adults, we additionally controlled for length of stay, dexamethasone use, and mechanical ventilation during the hospitalization