Variables a | Single group | Â | Repeated group |
---|
HR b (95% CI) | P value | Â | HR b (95% CI) | P value |
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Max SOFA | 1.12 (1.05–1.20) | < 0.001 |  | 1.09 (1.03–1.16) | 0.002 |
CCI | 1.13 (1.04–1.21) | 0.002 |  | 1.08 (1.00-1.15) | 0.039 |
SAPS-II | 1.02 (1.00-1.04) | 0.038 |  | 1.03 (1.01–1.04) | < 0.001 |
- a Max SOFA, CCI and SAPS-II were included as continuous variables in subgroup analysis of Cox proportional hazard regressions
- b HRs were adjusted for some statistically significant factors according to multivariate analysis (Max SOFA, CCI, SAPS-II, respiratory failure, length of ICU stay and immunosuppressants/biologics)
- Abbreviations: AD: autoimmune disease; CCI: Charlson comorbidity index; CI: confidence interval; HR: hazard ratio; SAPS-II: Simplified Acute Physiology Score-II; SOFA: Sequential Organ Failure Assessment