Table 3 Diagnostic accuracy of Truenat assay compared different bacteriological tests as reference comparator
Reference comparator (N) | Sensitivity n/N (%, 95%CI) | Specificity n/N (%, 95%CI) | PPV n/N (%, 95%CI) | NPV n/N (%, 95%CI) |
|---|---|---|---|---|
GeneXpert Ultra | 66/82 (80.5, 70.2–88.4) | 156/159 (98.1, 94.5–99.6) | 66/69 (95.6,87.8–99.1) | 156/172 (90.7, 85.3–94.6) |
LJ Culture | 50/64 (89.3, 66.0-87.4) | 166/180 (92.2, 87.2–95.6) | 50/64(78.1, 66.0-87.4) | 166/172 (96.5, 93.5–98.7) |
MGIT culture | 58/71 (81.7, 70.7–89.8) | 131/138 (94.9, 89.8–97.9) | 58/65 (89.2,79.0-95.5) | 131/144 (91.0, 85.0-95.1) |
LJ and/or MGIT | 59/73 (80.8, 69.9–89.1) | 159/169 (94.1, 89.3–97.1) | 59/69 (85.5, 74.9–92.8) | 159/173 (91.9, 86.7–95.5) |