characteristics | findings | remarks |
---|---|---|
Number of amino acids | 501 | suitable |
molecular weight | 54,059.97 Da | average |
Theoretical pI | 9.41 | basic |
chemical formula | C2455H3814N662O694S11 | –- |
extinction coefficient (at 280 nm in H2O) | 77,810 M−1 cm−1 | |
estimated half-life (mammalian reticulocytes, in vitro) | 30 h | satisfactory |
estimated half-life (yeast cells, in vivo) | > 20 h | satisfactory |
estimated half-life (E. coli, in vivo) | > 10 h | satisfactory |
instability index of vaccine | 34.63 | Stable |
aliphatic index of vaccine | 72.95 | thermostable |
grand average of hydropathicity (GRAVY) | -0.317 | hydrophilic |
antigenicity | 0.6455 (VaxiJen v2.0) 0.897722 (ANTIGENPro) | antigenic |
allergenicity | No (AllergenFP v1.0) No (AlgPred) No (AllerTop v2.0) | non-allergen |
solubility | 0.766196 (SolPro) 0.504 (Protein-Sol) | soluble |
TM helices | No | suitable |