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Table 2 Descriptive Statistics of Biomarker Values for the Definitive UTI and Definitive non-UTI Cohorts Based on Criterion 1

From: Urine biomarkers individually and as a consensus model show high sensitivity and specificity for detecting UTIs

 

Definitive UTI (Symptomatic)

 

Definitive Non-UTI (Asymptomatic)

 

No Microbes

 

With Microbes

SUC and M-PCR +

  

SUC or M-PCR +

SUC and M-PCR +

NGAL

(ng/mL)

n

351

 

110

 

118

51

Minimum

0.16

 

0.16

 

0.16

0.16

25th percentile

64.64

 

0.16

 

0.16

0.16

Median

211.09

 

0.16

 

0.16

9.51

75th percentile

500

 

0.16

 

17.65

27.04

Maximum

500

 

61.99

 

329.41

329.41

Mean

251.83

 

4.22

 

24.44

36.52

SD

193.96

 

11.33

 

56.79

70.24

Standard Error

10.35

 

1.08

 

5.23

9.84

Lower 95% CI

231.47

 

2.08

 

14.08

16.76

Upper 95% CI

272.19

 

6.36

 

34.79

56.27

IL-8

(pg/mL)

n

351

 

110

 

118

51

Minimum

0

 

0

 

0

0

25th percentile

109.12

 

0

 

0.38

0.15

Median

355.32

 

0.34

 

10.39

14.58

75th percentile

1206.36

 

3.07

 

46.98

52.46

Maximum

2000

 

1152.75

 

2000

466.02

Mean

693.47

 

15.57

 

61.65

46.53

SD

713.79

 

110.47

 

208.6

81.16

Standard Error

38.1

 

10.53

 

19.2

11.36

Lower 95% CI

618.54

 

-5.31

 

23.62

23.7

Upper 95% CI

768.4

 

36.44

 

99.69

69.35

IL-1β

(pg/mL)

n

351

 

110

 

118

51

Minimum

3.9

 

3.9

 

3.9

3.9

25th percentile

5.67

 

3.9

 

3.9

3.9

Median

47.07

 

3.9

 

3.9

3.9

75th percentile

204.32

 

3.9

 

3.9

3.9

Maximum

250

 

7.68

 

99.84

47.09

Mean

93.4

 

3.98

 

6.56

6.72

SD

97.81

 

0.53

 

11.69

8.8

Standard Error

5.22

 

0.05

 

1.08

1.23

Lower 95% CI

83.14

 

3.88

 

4.42

4.25

Upper 95% CI

103.67

 

4.08

 

8.69

9.2