Table 2 Genotype and allele distributions of candidate SNPs between the two groups (significance only)
From: Polymorphisms of IFN signaling genes and FOXP4 influence the severity of COVID-19
SNP | Genotype/Allele | Case (n = 64) | Control (n = 250) | Pa | OR(95%CI)b | Pb |
|---|---|---|---|---|---|---|
MX1 rs17000900 | CC | 54(84.4) | 180(72.0) | 0.089 | 1.000 | |
CA | 10(15.6) | 63(25.2) | 0.529(0.254–1.101) | 0.089 | ||
AA | 0(0.0) | 7(2.8) | - | - | ||
C | 118(92.2) | 423(84.6) | 0.027 | |||
A | 10(7.8) | 77(15.4) | ||||
FOXP4 rs1886814 | AA | 13(20.3) | 90(36.0) | 3.89E-04 | 1.000 | |
AC | 29(45.3) | 125(50.0) | 1.606(0.791–3.261) | 0.190 | ||
CC | 22(34.4) | 35(14.0) | 4.352(1.977–9.578) | 2.59E-04 | ||
A | 55(43.0) | 305(61.0) | 2.33E-04 | |||
C | 73(57.0) | 195(39.0) | ||||
FOXP4 rs2894439 | GG | 10(15.6) | 96(38.4) | 0.001 | 1.000 | |
GA | 35(54.7) | 113(45.2) | 2.973(1.400–6.317) | 0.005 | ||
AA | 19(29.7) | 41(16.4) | 4.449(1.904–10.393) | 0.001 | ||
G | 55(43.0) | 305(61.0) | 2.33E-04 | |||
A | 73(57.0) | 195(39.0) |