Table 2 The association of radiographic manifestations and baseline smear and culture positivity in all the mITT population of the STREAM stage 1 trial and stratified by HIV status
| Â | Total N (Col %) | Extent of opacity | Cavitation | ||||
|---|---|---|---|---|---|---|---|
Nil/minimal/moderate N (Col %) | Far advanced N (Col %) | P value1 | No N (Col %) | Yes N (Col %) | P value1 | ||
HIV positive participants | |||||||
 Participants | N = 118 | N = 71 | N = 47 | - | N = 23 | N = 95 | - |
 Smear | |||||||
  Negative/scanty/1+ | 44 (37) | 30 (42) | 14 (30) | 0.358 | 16 (70) | 28 (29) | 0.002 |
  2+ | 21 (18) | 11 (15) | 10 (21) | 2 (9) | 19 (20) | ||
  3+ | 53 (45) | 30 (42) | 23 (49) | 5 (22) | 48 (51) | ||
 Culture | |||||||
  Negative/1–9/1+ | 28 (24) | 15 (21) | 13 (28) | 0.292 | 10 (43) | 18 (19) | 0.023 |
  2+ | 40 (34) | 28 (39) | 12 (26) | 8 (35) | 32 (34) | ||
  3+ | 50 (42) | 28 (39) | 22 (47) | 5 (22) | 45 (47) | ||
HIV negative participants | |||||||
 Participants | N = 246 | N = 169 | N = 77 | - | N = 60 | N = 186 | - |
 Smear | |||||||
  Negative/scanty/1+ | 73 (30) | 51 (30) | 22 (29) | 0.364 | 22 (37) | 51 (27) | 0.003 |
  2+ | 67 (27) | 50 (30) | 17 (22) | 23 (38) | 44 (24) | ||
  3+ | 106 (43) | 68 (40) | 38 (49) | 15 (25) | 91 (49) | ||
 Culture | |||||||
  Negative/1–9/1+ | 55 (22) | 38 (22) | 17 (22) | 0.031 | 18 (30) | 37 (20) | 0.043 |
  2+ | 55 (22) | 30 (18) | 25 (32) | 17 (28) | 38 (20) | ||
  3+ | 136 (55) | 101 (60) | 35 (45) | 25 (42) | 111 (60) | ||