Radiographic characteristics of rifampicin-resistant tuberculosis in the STREAM stage 1 trial and their influence on time to culture conversion in the short regimen

Table 1 Comparison of radiographic characteristics and baseline smear and culture results in the mITT population of the STREAM stage 1 trial according to HIV status

	Total N = 364		HIV Positive N = 118		HIV Negative N = 246		P value¹
	N	Col %	N	Col %	N	Col %	P value¹
Upper opacity
No	17	5	7	6	10	4	0.435
Yes	347	95	111	94	236	96	0.435
Lower opacity
No	46	13	13	11	33	13	0.614
Yes	318	87	105	89	213	87	0.614
Right opacity
No	39	11	14	12	25	10	0.718
Yes	325	89	104	88	221	90	0.718
Left opacity
No	34	9	7	6	27	11	0.177
Yes	330	91	111	94	219	89	0.177
Isolated lower Opacity
No	348	96	112	95	236	96	0.785
Yes	16	4	6	5	10	4	0.785
Extent of opacity
Nil/minimal/moderate	240	66	71	60	169	69	0.125
Far advanced	124	34	47	40	77	31	0.125
Cavitation
Absent	83	23	23	19	60	24	0.351
Present	281	77	95	81	186	76	0.351
Location of cavities
None	83	23	23	19	60	24	0.499
Unilateral	158	43	51	43	107	44
Bilateral	123	34	44	37	79	32
Costophrenic obliteration
Absent	303	83	101	86	202	82	0.456
Present	61	17	17	14	44	18	0.456
Pleural thickening
Absent	348	96	112	95	236	96	0.785
Present	16	4	6	5	10	4	0.785
Smear
Negative/scanty/1+	117	32	44	37	73	30	0.110
2+	88	24	21	18	67	27
3+	159	44	53	45	106	43
Culture
Negative/1–9/1+	83	23	28	24	55	22	0.035
2+	95	26	40	34	55	22
3+	186	51	50	42	136	55

ISSN: 1471-2334