Table 5 Predictive power for Th17 cytokines Cut-off values for OHCV existence
From: Unraveling IL-17 and IL-22 role in occult hepatitis C versus chronic hepatitis C virus infection
Cytokine | AUROC (95%CI) | Sensitivity (95%CI) | Specificity (95%CI) | Accuracy (95%CI) | PPV (95%CI) | NPV (95%CI) |
|---|---|---|---|---|---|---|
IL-17 (≤ 32.1) | 0.829(0.732–0.902 | 51.4(34-68.6) | 96 (86.3–99.5) | 77.6 (68.2–81.5) | 90 (69.8–98.2) | 73.8 (67.6–76.4) |
IL-22 (≤ 14.3) | 0.504 (0.393 -0.614) | 65.7(47.8–80.9) | 48 (33.7- 62.6) | 55.3 (43.8–65.7) | 46.9 (37–56) | 66.7 (53.1–78.9) |