A regimen based on the combination of trimethoprim/sulfamethoxazole with caspofungin and corticosteroids as a first-line therapy for patients with severe non-HIV-related pneumocystis jirovecii pneumonia: a retrospective study in a tertiary hospital

Table 5 Change of inflammatory biomarkers and ventilator parameters after the utilization of GCS

Parameters	0 day of the utilization of GCS	3 days after the utilization of GCS	P
Interleukin-6, pg/mL, [median (IQR)]	268.00(23.74–482.90)	43.00(25.00–56.00)	0.040*
C-reactive protein, mg/L, [median (IQR)]	66.70(54.20–168.00)	67.00(43.00–90.00)	0.619
Ventilator parameters
V_T, ml/kg(PBW)[median (IQR)]	5.40(5.00-6.30)	5.40(5.20–6.10)	0.095
PEEP median, cmH₂O [median (IQR)]	10.00(8.00–11.00)	8.00(8.00–10.00)	0.189
Plateau pressure, cmH₂O median (IQR)]	22.00(20.00–28.00)	21.00(18.00–23.00)	0.196
Driving pressure, cmH₂O [median (IQR)]	12.00(11.00–16.00)	12.00(9.00–15.00)	0.271

ISSN: 1471-2334