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Table 3 Clinical characteristics of the cases in ST group

From: A regimen based on the combination of trimethoprim/sulfamethoxazole with caspofungin and corticosteroids as a first-line therapy for patients with severe non-HIV-related pneumocystis jirovecii pneumonia: a retrospective study in a tertiary hospital

Case

Age, year

Gender

Underlying condition

Tracheal intubation

ECMO

CRRT

Co-infection/Location

Duration of Caspo, day

MP,

mg/kg/day

Duration of MP,

day

Outcome

1

59

M

Renal transplantation

Y

N

N

CMV/Lung

17

1.16

7

Survived

2

59

F

Nephropathy

Y

N

N

KP/Lung

22

1.51

7

Survived

3

62

M

acute myeloid leukemia

Y

N

Y

PA/Lung

21

1.36

5

Survived

4

62

M

Vasculitis

Y

N

N

C. albicans /Lung

15

1.23

8

Survived

5

76

M

Polymyositis

Y

N

N

MRSA /Lung

24

0.62

5

Survived

6

51

M

Renal transplantation

N

N

Y

E. coli/urinary tract

16

1.67

3

Survived

7

25

M

Lupus erythematosus

Y

N

N

 

27

1.54

5

Survived

8

36

M

Renal transplantation

Y

Y

N

CMV/Lung

23

0.65

5

Survived

9

79

M

Herpes zoster

Y

N

Y

CRAB/Lung and blood

31

1.07

7

Died

10

34

M

Renal transplantation

N

N

Y

 

25

0.53

7

Survived

11

54

M

acute myeloid leukemia

Y

N

Y

CMV/Lung

12

0.58

5

Survived

12

65

M

acute myeloid leukemia

Y

Y

N

CRAB/Lung

31

0.65

14

Survived

13

64

F

Lupus erythematosus

Y

Y

Y

HPV type IV /Lung + EF/Blood

36

0.42

5

Survived

14

50

F

Renal transplantation

Y

N

N

HPV type I I/Lung

9

1.60

9

Died

15

54

M

acute myeloid leukemia

Y

N

N

 

5

0.66

5

Died

16

47

M

Renal transplantation

N

N

N

CMV + HPV type IV/Lung

8

0.24

7

Survived

17

49

F

Renal transplantation

N

N

N

CMV/Lung

29

0.77

7

Survived

18

19

F

Renal transplantation

N

N

N

SARS-CoV-2/Lung

7

0.40

5

Survived

19

56

F

Renal transplantation

Y

Y

Y

MRSA/Lung

31

0.72

10

Died

20

38

F

Renal transplantation

Y

N

Y

CMV + EBV + VZV/Lung

6

0.73

3

Died

  1. Caspo, Caspofungin; CMV, Cytomegalovirus; VZV, Human alphaherpesvirus; EBV, Human gammaherpesvirus 4; HPV, Human herpesvirus; KP, Klebsiella pneumoniae; PA, Pseudomonas aeruginosa; C. albicans, Candida albicans; MRSA, Methicillin-resistant Staphylococcus aureus; EF, Enterococcus faecium; E. coli, Escherichia coli; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; CRAB, Carbapenem Resistance Acinetobacter Baumannii; MP, methylprednisolone