Table 3 Demographic characteristics, comorbid conditions, clinical symptoms, and laboratory parameters of SFTS patients with and without SIRS

Male, n (%)

90(54.9)

57(45.2)

0.104

Age (years)

65(59–70)

66(58–69)

0.198

Diabetes, n (%)

14(8.5)

9(7.1)

0.663

Hypertension, n (%)

42(25.6)

29(23.0)

0.611

Days from onset to admission

6(5–7)

6(5–8)

0.864

Clinical manifestations, n (%)

 Neurological

  Headache

27(16.5)

28(22.2)

0.215

  Dizziness

50(30.5)

45(35.7)

0.347

  Encephalopathy

16(9.8)

29(23.0)

0.002

 Respiratory

  Cough

30(18.3)

37(29.3)

0.027

  Sputum

23(14.0)

36(28.6)

0.002

  Chest distress

32(19.5)

27(21.4)

0.688

 Gastrointestinal

  Anorexia

112(68.3)

100(79.4)

0.035

  Nausea

110(67.1)

82(65.1)

0.722

  Vomiting

52(31.7)

39(31.0)

0.891

  Abdominal pain

25(15.2)

23(18.3)

0.494

  Diarrhea

39(23.8)

31(24.6)

0.871

Laboratory parameters

 WBC (10⁹/L)

4.4(2.6–6.6)

2.9(1.7–5.4)

0.001

 Neutrophils (10⁹ /L)

2.9(1.2–5.1)

1.8(1.0–4.0)

0.028

 Neutrophils (%)

69.0(51.1–82.5)

69.1(57.1–81.8)

0.705

 Lymphocyte (10⁹/L)

0.8(0.5–1.2)

0.6(0.4–1.1)

0.093

 Lymphocyte (%)

19.8(11.4–32.8)

23.2(13.8–32.7)

0.331

 Platelet (10⁹ /L)

43(29–63)

40(27–56)

0.061

 Hemoglobin (g/L)

123 ± 18

124 ± 20

0.220

 ALT (U/L)

73(47–117)

74(44–130)

0.868

 AST (U/L)

149(67–369)

196(101–426)

0.017

 TBIL(μmol/L)

11.4(8.1–17.4)

12.1(9.4–17.8)

0.221

 Albumin (g/L)

30.0 ± 5.2

30.0 ± 4.4

0.788

 Globulin (g/L)

26.1(23.4–29.6)

25.4(23.2–29.4)

0.298

 ALP (U/L)

72(57–94)

76(57–111)

0.223

 GGT (U/L)

41(24–88)

34(21–103)

0.920

 LDH (U/L)

585(326–943)

715(449–1000)

0.013

 Amylase (U/L)

146(95–220)

162(104–256)

0.044

 Lipase (U/L)

149(79–280)

191(99–379)

0.013

 BUN (mmol/L)

5.3(3.9-7.0)

5.4(3.8–8.1)

0.389

 Creatinine (μmol/L)

71(61–96)

75(64–104)

0.063

 Cystatin-C (mg/L)

1.2(0.9–1.5)

1.2(1.0-1.7)

0.125

 Sodium (mmol/L)

135.7(132.6-138.2)

134.2(131.0-137.5)

0.117

 Potassium (mmol/L)

3.6(3.3-4.0)

3.6(3.3–4.1)

0.560

 CK (U/L)

251(89–853)

473(216–1127)

0.001

 CK-MB (U/L)

26(13–43)

38(20–58)

0.001

 Troponin I (pg/mL)

83.9(36.3-163.8)

132.1(42.8-317.5)

0.020

 BNP (pg/mL)

65.6(19.6-169.2)

84.1(26.6-194.2)

0.327

 PT (s)

11.3(10.6–12.0)

11.4(10.7–12.1)

0.660

 INR

1.04(0.97–1.10)

1.04(0.99–1.12)

0.511

 PTA (%)

98(88–109)

99(86–111)

0.877

 APTT(s)

39.3(33.3–47.3)

42.2(36.8–51.2)

0.008

 TT(s)

17.3(15.8–19.7)

18.4(16.2–22.1)

0.008

 Fibrinogen (mg/dL)

260(200–312)

235(190–281)

0.010

 D-dimer (ng/mL)

870(394–2195)

1247(610–2437)

0.034

 CRP (mg/L)

4.2(2.8–9.8)

8.8(4.9–20.6)

0.015

 Procalcitonin (ng/mL)

0.20(0.06–0.53)

0.26(0.09–0.91)

0.088

 IL-6 (pg/mL)

22.1(14.2–39.3)

29.1(16.8–76.1)

0.001

 SAA (mg/L)

34.5(23.6–74.9)

49.9(25.5-167.3)

0.004

 ESR (mm/h)

8(5–14)

9(5–14)

0.623

 Ferritin (ng/mL)

3028(2261–4957)

3589(2475–5786)

0.063

 Viral load (log₁₀ copies/mL)

3.8(3.4–4.4)

4.2(3.5–4.8)

0.002