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Table 7 Syphilis POCTs results compared to TPPA and RPR titres (does not include Peruvian sites)

From: Independent clinic-based evaluation of dual POCTs for screening for HIV and syphilis in men who have sex with men in Italy, Malta, Peru, and the United Kingdom

Titres

POCT result % agreement with reference test

TPPA + 

RPR

Bioline

Chembio

Chembio MR

 ≥ 20,480

 + 

256

 

128

100% (1/1)

100% (1/1)

100% (1/1)

64

100% (3/3)

100% (3/3)

100% (3/3)

32

100% (3/3)

100% (3/3)

100% (3/3)

16

100% (5/5)

100% (5/5)

100% (5/5)

8

100% (5/5)

100% (5/5)

100% (5/5)

4

100% (9/9)

100% (9/9)

88.89% (8/9)

2

92.86% (13/14)

92.86% (13/14)

85.71% (12/14)

1

100% (3/3)

100% (3/3)

100% (3/3)

2560–10240

 + 

256

100% (44)

100% (4/4)

100% (4/4)

128

   

64

100% (4/4)

100% (4/4)

100% (4/4)

32

100% (6/6)

100% (6/6)

100% (6/6)

16

100% (5/5)

100% (5/5)

100% (5/5)

8

90% (9/10)

90% (9/10)

95.24% (10/10)

4

100% (13/13)

100% (13/13)

100% (13/13)

2

90.91% (10/11)

100% (11/11)

100% (11/11)

1

94.74% (18/19)

94.74% (18/19)

89.47% (17/19)

80–1280

 + 

256

 

128

   

64

100% (1/1)

100% (1/1)

100% (1/1)

32

100% (1/1)

100% (1/1)

100% (1/1)

16

   

8

100% (1/1)

100% (1/1)

100% (1/1)

4

75% (3/4)

100% (4/4)

100% (4/4)

2

50% (6/12)

50% (6/12)

66.67% (8/12)

1

45.45% (5/11)

45.45% (5/11)

54.55% (6/11)

 ≥ 20,480

-

0

87.10% (27/31)

87.10% (27/31)

87.10% (27/31)

2560–10240

-

0

73.74% (73/99)

79.80% (79/99)

82.83% (82/99)

80–1280

-

0

27.66% (39/141)

36.17% (51/141)

40.43% (57/141)