Skip to main content

Table 5 Pooled performance characteristics of POCTs for syphilis compared to reference assays

From: Independent clinic-based evaluation of dual POCTs for screening for HIV and syphilis in men who have sex with men in Italy, Malta, Peru, and the United Kingdom

POCT

Pooled Sensitivity

Pooled Specificity

Prevalence Scenarios a

PPV

NPV

Bioline

73.79%

99.57%

18.88%

97.56%

94.23%

  

23.88%

98.18%

92.37%

  

53,79%

99.50%

76.55%

  

58,79%

99.59%

72.70%

Chembio

78.60%

99.48%

18.88%

97.24%

95.23%

  

23.88%

97.93%

93.68%

  

53,79%

99.43%

79.97%

  

58,79%

99.54%

76.52%

Chembio MR (Micro Reader)

80.10%

99.01%

18.88%

94.96%

95.53%

  

23.88%

96.21%

94.07%

  

53,79%

98.95%

81.04%

  

58,79%

99.14%

77.72%

  1. aActual prevalence range (min–max from sites): 23.88%-53,79%