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Table 3 Pooled performance characteristics of POCTs for HIV compared to reference assays

From: Independent clinic-based evaluation of dual POCTs for screening for HIV and syphilis in men who have sex with men in Italy, Malta, Peru, and the United Kingdom

POCT

Pooled Sensitivity

Pooled Specificity

Prevalence Scenariosa

PPV

NPV

Bioline

98.95%

99.89%

5.60%

98.16%

99.94%

  

10.60%

99.07%

99.88%

  

35.60%

99.80%

99.42%

  

40.60%

99.84%

99.29%

Chembio

98.66%

99.55%

5.60%

92.86%

99.92%

  

10.60%

96.30%

99.84%

  

35.60%

99.18%

99.26%

  

40.60%

99.34%

99.09%

Chembio MR (Micro Reader)

98.09%

99.54%

5.60%

92.67%

99.89%

  

10.60%

96.20%

99.77%

  

35.60%

99.16%

98.95%

  

40.60%

99.32%

98.70%

  1. aActual prevalence range (min–max from sites): 10.6%-35.6%