Table 3 Calculated sensitivity and specificity (and 95% confidence intervals) for the GeneXpert (using random effects model)

Chlamydia

 Country

Valid Cases

Sensitivity (95% Confidence Intervals)

Specificity (95% Confidence Intervals)

  Morocco

383

70.1% (58.6–80.0)

97.7% (95.3–99.1)

  Guatemala (Site 1)

86

82.4% (56.6–96.2)

100% (94.8–100)

  South Africa

785

91.4% (87.6–94.3)

96.9% (95.0-98.3)

  Pooled estimate

1254

83.7% (69.2–92.1)

97.4% (96.1-98.3%)

Gonorrhoea

 Country

Valid Cases

Sensitivity (95% Confidence Intervals)

Specificity (95% Confidence Intervals)

  Morocco

388

90.9% (58.7–99.8)

99.7% (98.5–100)

  Guatemala (Site 1)

86

100% (15.8–100)

98.8% (93.5–100)

  South Africa

779

90.4% (84.6–94.5)

98.4% (97.1–99.2)

  Pooled estimate

1253

90.5% (85.1–94.1)

99.1% (97.6–99.6)

Trichomoniasis

 Country

Valid Cases

Sensitivity (95% Confidence Intervals)

Specificity (95% Confidence Intervals)

  Morocco

393

59.7% (51.5–67.6)

98.8% (96.4–99.8)

  Guatemala (Site 1)

84

91.7% (61.5–99.8)

100% (95.1–100)

  South Africa

786

66.1% (57.1–74.4)

98.8% (97.6–99.5)

  Australia

69

84.6% (54.6–98.1)

100% (94.6–100))

  Pooled estimate

1332

64.7% (58.1–70.7)

99.0% (98.1–99.4)