Table 3 Demographic and clinical characteristics associated with clarithromycin resistance in our cohort
From: In vitro susceptibility of nontuberculous mycobacteria in China
Characteristics | No. of isolates n = 244 (%) | Clarithromycin | OR (95%CI) | P value | |
|---|---|---|---|---|---|
Susceptiblen = 192(79%) | Resistant n = 52(21%) | ||||
Sex | |||||
Male | 124(51) | 94(49) | 30(58) | 1.000 | Reference |
Female | 120(49) | 98(51) | 22(42) | 0.969(0.525~1.789) | 0.920 |
Age, year | |||||
<45 | 26(9) | 20(10) | 6(10) | 1.000 | Reference |
45–65 | 127(42) | 98(51) | 29(56) | 2.500(0.934~6.692) | 0.068 |
> 65 | 91(48) | 74(38.5) | 17(33) | 1.408(0.695~2.853) | 0.343 |
Treatment history | |||||
New cases | 125(51) | 96(50) | 29(56) | 1.000 | Reference |
Retreated cases | 119(49) | 96(50) | 23(44) | 1.248(0.674~2.311) | 0.482 |
Complication | |||||
COPD | 31(13) | 23(12) | 8(15) | 0.796(0.333~1.901) | 0.607 |
Bronchiectasis | 103(42) | 79(41) | 24(46) | 0.895(0.482~1.662) | 0.725 |
Asthma | 6(2) | 4(2) | 2(4) | 0.568(0.101~3.193) | 0.521 |
Diabetes | 28(11) | 19(10) | 9(17) | 0.568(0.237~1.326) | 0.188 |
HIV | 10(4) | 8(4) | 2(4) | 1.170(0.241~5.685) | 0.846 |
Clinical symptoms | |||||
Cough | 82(34) | 71(37) | 11(21) | 0.181(0.024~1.388) | 0.100 |
Hemoptysis | 4(2) | 3(2) | 1(2) | 0.581(0.278~1.214) | 0.149 |
Fever | 12(5) | 11(6) | 1(2) | 0.429(0.211~0.873) | 0.020 |
Thoracalgia | 7(3) | 6(3) | 1(2) | 0.754(0.298~1.906) | 0.551 |