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Table 4 Univariate and multivariate Logistic analysis of 28-day mortality in patients with sepsis

From: Bisphosphoglycerate mutase predicts myocardial dysfunction and adverse outcome in sepsis: an observational cohort study

Variables

Univariate analysis

Multivariate analysis

OR(95%CI)

P

Adjusteda OR(95%CI)

P

Gender

 Male

1 (reference)

-

  

 Female

0.68 (0.26–1.8)

0.442

  

Age, years

 < 65

1 (reference)

-

  

 ≥ 65

1.11 (0.43–2.89)

0.828

  

APACHE II, score

 < 24

1 (reference)

-

1 (reference)

-

 ≥ 24

18.17 (3.91–84.55)

< 0.001

2.60(0.300–22.546)

0.386

SOFA, score

    

 < 7

1 (reference)

-

  

 ≥ 7

1.49 (0.55–3.99)

0.433

  

BPGM, ng/ml

 < 0.312

1 (reference)

-

1 (reference)

-

 ≥ 0.312

10.69 (3.42–33.36)

< 0.001

9.853(1.844–52.655)

0.007

Lactate, mmol/l

 < 3.3

1 (reference)

-

  

 ≥ 3.3

2.21 (0.82 ~ 5.92)

0.116

  

PCT, ng/ml

 < 0.5

1 (reference)

-

  

 ≥ 0.5

0.78 (0.07–9.02)

0.842

  

LDH, IU/l

 < 246

1 (reference)

-

  

 ≥ 246

2.14 (0.7–6.54)

0.18

  

AG,mmol/l

 < 18.5

1 (reference)

-

  

 ≥ 18.5

2.02 (0.77–5.26)

0.152

  

CK, IU/l

 < 201

1 (reference)

-

  

 ≥ 201

0.76 (0.29–1.99)

0.571

  

CK-MB, ng/ml

 < 31

1 (reference)

-

  

 ≥ 31

1.4 (0.54–3.63)

0.492

  

NT-proBNP, pg/ml

 < 900

1 (reference)

-

  

 ≥ 900

5.06 (0.62–41.53)

0.131

  

cTnI, ng/ml

 < 0.075

1 (reference)

-

1 (reference)

-

 ≥ 0.075

6.28 (2.06–19.11)

0.001

1.024(0.115–9.073)

0.978

LVEF-S,%

 < 48

1 (reference)

-

1 (reference)

-

 ≥ 48

0.01 (0–0.07)

< 0.001

0.032(0.002–0.43)

0.009

Tei Index

 < 0.48

1 (reference)

-

1 (reference)

-

 ≥ 0.48

43.81 (5.52–347.4)

< 0.001

4.319(0.201–92.751)

0.35

  1. Bold values indicate P < 0.05
  2. APACHE II Acute Physiology and Chronic Health Evaluation II score, SOFA Sequential Organ Failure Assessment, BPGM bisphosphoglycerate mutase, PCT procalcitonin, LDH Lactate dehydrogenase, AG Anion gap, CK Creatine kinase, CK-MB Creatine kinase-MB, NT-proBNP N-terminal-probrain natriuretic peptide, cTnI cardiac troponin I, LVEF-S left ventricular ejection fraction-simpson, Tei Index myocardial performance index, IQR interquartile range
  3. aAdjusted for all other variables in model